Evidence map›Paper›PMID 31344797›Full record

ArticleMaterials (Basel, Switzerland)2019

Periorbital Reconstruction by "Periorbital Patch" Technique Using a Pericardium-Based Collagen Membrane and Titanium Mesh.

Nenad Tanaskovic, Branko Trajkovski, Željka Perić Kačarević, Patrick M Rider, Alireza Houshmand, Xin Xiong, Ole Jung, Mike Barbeck

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Nenad TanaskovicClinic of Maxillofacial Surgery, Clinical Centre, 78000 Banja Luka, Herzegovina. tanaskovicn@yahoo.com.
Branko TrajkovskiWound Healing and Oral Diagnostic Research Group, College of Dental Medicine, University of Sharjah, 27272 Sharja, UAE.ORCID 0000-0003-4161-5645
Željka Perić KačarevićDepartment of Anatomy Histology, Embryology, Pathology Anatomy and Pathology Histology, Faculty of Dental Medicine and Health, University of Osijek, 31000 Osijek, Croatia.
Patrick M RiderBotiss Biomaterials GmbH, 15806 Zossen, Germany.ORCID 0000-0002-3620-7199
Alireza HoushmandDepartment of Anatomy Histology, Embryology, Pathology Anatomy and Pathology Histology, Faculty of Dental Medicine and Health, University of Osijek, 31000 Osijek, Croatia.
Xin XiongNatural and Medical Sciences Institute, University of Tübingen, 72770 Reutlingen, Germany.
Ole JungDepartment of Oral and Maxillofacial Surgery, Division for Regenerative Orofacial Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Mike BarbeckDepartment of Oral and Maxillofacial Surgery, Division for Regenerative Orofacial Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.ORCID 0000-0002-3001-1347
Carl Zeiss (Germany) · DEUniversität Hamburg · DEUniversity of Osijek · HRNatural and Medical Sciences Institute · DEUniversity Clinical Centre · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTitanium mesh is a commonly used material for the reconstruction of orbital floor fractures. However, in some instances, a subsequent inflammatory reaction can occur that causes the adhesion of orbital tissue to the titanium mesh. The adhesion of the orbital soft tissue to the mesh causes diplopia, lid rigidity and extraocular movements restriction. This study was performed to determine if the placement of a collagen membrane over a titanium mesh can prevent the adhesion of orbital soft tissue for an improved clinical outcome. Clinical considerations: A case study was performed investigating 106 patients undergoing a periorbital restoration. Seventy-two patients received a titanium mesh without a barrier membrane, 12 patients received a barrier membrane composed of autologous auricular cartilage to provide a barrier function and 22 patients received a pericardium collagen membrane and titanium mesh.

conclusionsTitanium has been shown to generate an intense inflammatory reaction in host tissues, which can cause fibrosis to adjacent structures. Fibrosis is an essential factor in the repair of fracture sites, however this can lead to adverse effects in the orbital socket. Fibrosis can cause cicatrization and lower eyelid retraction when induced along the lower orbital rim. An improved outcome can be achieved by using a barrier between the titanium mesh and the soft tissue, such as autogenous auricular cartilage, however, only patients treated with a resorbable collagen membrane to act as a soft tissue barricade during site regeneration, prevented the fibrosis reaction and related problems from occurring.

Indexed as

collagen membranefibrosisorbital adherence syndromeperiosteumtitanium mesh

Identifiers

PMID31344797
PMCPMC6696015
OpenAlexW2964071975

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.