ArticleJournal of thrombosis and haemostasis : JTH2019
Quality of life and functional limitations after pulmonary embolism and its prognostic relevance.
Article in Journal of thrombosis and haemostasis : JTH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07143539 (Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority Trial
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Patient-Reported Outcomes in Venous Thromboembolism: A Systematic Review of the Literature, Current Challenges, and Ways Forward.Journal of the American Heart Association · 2023Pooled it
- Improving health literacy of patients with pulmonary embolism through evidence-based health information: a feasibility study.Frontiers in public health · 2026Trial
- Personalized approach to high-risk and intermediate-high-Risk pulmonary embolism in older adults.Intensive care medicine · 2026Article
- Fatigue after pulmonary embolism-prevalence and predictors.Frontiers in cardiovascular medicine · 2026Article
- Article
- How I treat pediatric pulmonary embolism.Blood · 2025Review
- Assessing Health-Related Quality of Life of Patients with Pulmonary Embolism with the Heart QoL Questionnaire.Medicina (Kaunas, Lithuania) · 2025Article
- The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism.Research and practice in thrombosis and haemostasis · 2025Article
- Psychological Impact of Pulmonary Embolism: A Narrative Review.Journal of community hospital internal medicine perspectives · 2025Review
- Dyspnea after a first episode of pulmonary embolism: prevalence, predictors and long-term associations with health-related quality of life.Frontiers in cardiovascular medicine · 2025Article
- 3-year quality of life, functional performance, and long-term survival after acute pulmonary embolism; A prospective study.Pulmonary circulation · 2024Article
- Review
- Comparisons of clinical scoring systems among suspected pulmonary embolism patients presenting to emergency department.Health science reports · 2024Article
- Association between Mid-Term Functionality and Clinical Severity in Patients Hospitalized for Pulmonary Embolism.Healthcare (Basel, Switzerland) · 2024Article
- Association between severity of pulmonary embolism and health-related quality of life.Journal of thrombosis and haemostasis : JTH · 2024Article
- Prevalence of long-term right ventricular dysfunction after acute pulmonary embolism: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- First use of large-bore suction thrombectomy for acute pulmonary embolism in Asia-Pacific: feasibility and short-term clinical outcomes.Journal of thrombosis and thrombolysis · 2023Article
- Mental Health and Quality of Life in Pulmonary Embolism: A Literature Review.Advances in respiratory medicine · 2023Review
- Cross-cultural validity of the Pulmonary Embolism Quality of Life questionnaire in the quality of life survey after pulmonary embolism: A Persian-speaking cohort.Research and practice in thrombosis and haemostasis · 2023Article
- Mansoor's Self-Report Tool for Cardiovascular Risk Assessment predicts adverse in-hospital events in patients with pulmonary embolism.The clinical respiratory journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile the importance of patients' quality of life (QoL) in chronic cardiac or pulmonary disease is uncontroversial, the burden of an acute pulmonary embolism (PE) on QoL has received little attention thus far.
objectivesWe aimed to validate the German PEmb-QoL questionnaire, identify associations between QoL and clinical/functional parameters, and investigate the prognostic relevance of QoL for long-term survival in survivors of an acute PE episode. PATIENTS/
methodsPatients were invited for a clinical follow-up visit including assessment of QoL using the German PEmb-QoL questionnaire 6 months after an objectively confirmed PE at a single center. Internal consistency reliability, construct-related validity, and regressions between PEmb-QoL and clinical patient-characteristics were assessed using standard scale construction techniques.
resultsOverall, 101 patients [median age, 69 ([interquartile range] IQR 57-75) years; women, 48.5%] were examined 208 (IQR 185-242) days after PE. Internal consistency reliability and construct-related validity of the PEmb-QoL questionnaire were acceptable. As many as 47.0% of patients reported dyspnea, 27.5% had right ventricular (RV) dysfunction on transthoracic echocardiography (TTE), and 25.3% were diagnosed with post-PE impairment (PPEI) at 6-month follow-up. Furthermore, 15.9% of patients were diagnosed with depression 6 months after an acute PE. The QoL was affected by dyspnea, preexisting pulmonary disease, and PPEI, and a reduced QoL was associated with an increased risk for long-term mortality after an observation period of 3.6 years.
conclusionsThe German PEmb-QoL questionnaire is a reliable instrument for assessing QoL 6 months after PE. The QoL was affected by dyspnea, preexisting pulmonary disease, and PPEI and was associated with long-term mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.