Evidence map›Paper›PMID 31344259›Full record

ReviewFEBS letters2019

Lipid-dependent coupling of secretory cargo sorting and trafficking at the trans-Golgi network.

Julia von Blume, Angelika Hausser

Open access · bronzeAbstract readReview
In one paragraph

Review in FEBS letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 55 citations in OpenAlex.

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  8. Dual membrane-spanning anti-sigma factors regulate vesiculation inProceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Julia von BlumeDepartment of Cell Biology, Yale School of Medicine, New Haven, CT, USA.
Angelika HausserInstitute of Cell Biology and Immunology, University of Stuttgart, Germany.ORCID 0000-0002-4102-9286
University of Stuttgart · DEYale University · US

Funding

Mechanism of secretory cargo export from the TGNR01GM134083 · NIGMS · YALE UNIVERSITY · PI VON BLUME, JULIA · 2019 to 2022
$1.5M
Deutsche Forschungsgemeinschaft DFG HA 3557/11-2German Cancer Foundation 70111941NIGMS NIH HHS R01 GM134083Perspective Program (Boehringer Ingelheim Foundation) BL 1186/4-1Perspective Program (Boehringer Ingelheim Foundation) CRC914 (TP A09)
6 · The paper itself

Abstract

In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key functions. This review addresses the role of lipids at the TGN with a particular emphasis on sphingolipids and diacylglycerol. We further highlight how these lipids couple secretory cargo sorting and trafficking for spatiotemporal coordination of protein transport to the plasma membrane.

Indexed as

Lipid MetabolismAnimalsBiological TransportHumanstrans-Golgi Networkdiacylglycerolsecretory cargo sortingsphingolipidstraffickingtrans-Golgi network

Identifiers

PMID31344259
PMCPMC8048779
OpenAlexW2964321733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.