Evidence map›Paper›PMID 31344108›Full record

ArticlePloS one2019

Factors associated with atypical radiological findings of pulmonary tuberculosis.

Akihiko Goto, Kosaku Komiya, Takamasa Kan, Kokoro Honjo, Sonoe Uchida, Shuichi Takikawa, Tetsuyuki Yoshimatsu, Kiminori Fujimoto, Takeshi Johkoh, Jun-Ichi Kadota

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Akihiko GotoInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Kosaku KomiyaInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.ORCID 0000-0002-8679-1661
Takamasa KanInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Kokoro HonjoInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Sonoe UchidaInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Shuichi TakikawaInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Tetsuyuki YoshimatsuInternal Medicine, National Hospital Organization Nishi-Beppu Hospital, Tsurumi, Beppu, Oita, Japan.
Kiminori FujimotoRadiology, Kurume University School of Medicine, 67-Asahimachi, Kurume, Japan.
Takeshi JohkohRadiology, Kansai Rosai Hospital, Inabasou, Amagasaki, Hyogo, Japan.
Jun-Ichi KadotaRespiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine, Idaigaoka, Hasama-machi, Yufu, Oita, Japan.
Oita University · JPBeppu Medical Center · JPKansai Rosai Hospital · JPKurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnusual radiological images may delay diagnosis of pulmonary tuberculosis. This study aimed to analyze the risk factors for an atypical radiological image in patients with pulmonary tuberculosis.

methodsWe retrospectively analyzed data from patients admitted to one hospital from January 2013 to December 2016 for sputum smear-positive lung tuberculosis who underwent chest computed tomography (CT) on admission. Patients whose sputum cultures were positive for general bacteria were excluded. Patient characteristics and laboratory data were compared between patients with cavity and those without and between patients with upper predominant lung involvement and those without.

resultsThis study included 94 (93%) of 101 patients who underwent chest CT. The non-cavity group was older, had a greater number of females, had a lower C-reactive protein (CRP) level, and had a lower glomerular filtration rate. Multivariate analysis showed that a low CRP level (OR 0.808; 95% CI 0.674-0.967; p = 0.020) significantly predicted non-cavity pulmonary tuberculosis. The non-upper predominant lung involvement group was older and had a greater number of females, poorer performance status, a higher CRP level, and a lower serum albumin level. A poor performance status (OR 2.155; 95% CI 1.257-3.693; p = 0.005) was found to significantly predict pulmonary tuberculosis with non-upper predominant lung distributions.

conclusionsA low CRP level and poor performance status were associated with non-cavity and non-upper predominant lung distribution, respectively, in patients with pulmonary tuberculosis. Tuberculosis patients with these characteristics may present unusual chest images.

Indexed as

AgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiography, ThoracicRetrospective StudiesRisk FactorsSputumTomography, X-Ray ComputedTuberculosisTuberculosis, Pulmonary

Identifiers

PMID31344108
PMCPMC6657914
OpenAlexW2964063837

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.