Evidence map›Paper›PMID 31344077›Full record

Trial reportPloS one2019

Stress response in the daily lives of simulation repeaters. A randomized controlled trial assessing stress evolution over one year of repetitive immersive simulations.

Daniel Aiham Ghazali, Cyril Breque, Philippe Sosner, Mathieu Lesbordes, Jean-Jacques Chavagnat, Stéphanie Ragot, Denis Oriot

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02424890 (Trial of Multidisciplinary Team Stress and Performance in Immersive Simulation for Management of Infant in Shock), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02424890 nacompletednot on this map

Trial of Multidisciplinary Team Stress and Performance in Immersive Simulation for Management of Infant in Shock

TypeinterventionalSponsorPoitiers University HospitalRan2013Enrolled48ConditionsStressArmsMDT simulation sessions of management of life-threatening events over 1 year
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Daniel Aiham GhazaliEmergency Department and Emergency Medical Service, University Hospital of Bichat, Paris, France.ORCID 0000-0003-0129-4322
Cyril BrequeABS Lab, Simulation Center, Faculty of Medicine, University of Poitiers, Poitiers, France.
Philippe SosnerDiagnosis and Therapeutic Center, University Hospital Hôtel-Dieu, Paris, France.
Mathieu LesbordesCardiology Department, University Hospital of Poitiers, Poitiers, France.ORCID 0000-0003-3132-8781
Jean-Jacques ChavagnatAdult Psychiatric Unit, Hospital of Poitiers, Poitiers, France.
Stéphanie RagotStatistical Department and Clinical Investigation Center (CIC 1402), INSERM (French National Health and Medical Research Institute), University Hospital of Poitiers, Poitiers, France.
Denis OriotABS Lab, Simulation Center, Faculty of Medicine, University of Poitiers, Poitiers, France.
Université de Poitiers · FRDélégation Paris 7 · FRHôtel-Dieu de Paris · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSimulations in healthcare reproduce clinical situations in stressful conditions. Repeated stress exposure might influence the learning process in simulation as well as real-life.

objectives1) To record heart rate and heart rate variability evolution during one-day simulation over one year; 2) To analyze the effect of repetitive high-fidelity simulations on the risk of post-traumatic stress disorder. STUDY

designSingle-center, investigator-initiated RCT. 48 participants were randomized in 12 multidisciplinary teams of French Emergency Medical Services to manage infant shock in high-fidelity simulations. In the experimental group, 6 multidisciplinary teams were exposed to 9 different simulation sessions over 1 year. In the control group, 6 multidisciplinary teams participated in only 3 simulation sessions, in common with those of the experimental group (initial, intermediate after 6 months, and finally after 1 year). Heart rate (HR) and heart rate variability (HRV) were analyzed on a 24-hour Holter from the day prior to simulation until the end of simulation. Questionnaires of Impact of Event Scale-Revised at 7 days and Post-traumatic Check-List Scale at 1 month were used to detect possible post-traumatic stress disorder in participants. p<0.05 was considered significant.

resultsStress increased during each simulation in the two groups. After analysis on the 24-hour period, there was no significant difference between the two groups during the initial simulation session in terms of heart rate and heart rate variability. In the 24-hour period of the intermediate and final simulation sessions, the level of stress was higher in the control group during the diurnal (p = 0.04) and nocturnal periods (p = 0.01). No participant developed post-traumatic stress disorder after the 72 simulation sessions.

conclusionsDespite the stress generated by simulation, the more the sessions were repeated, the less were their repercussions on the daily lives of participants, reflected by a lower sympathetic activity. Moreover, repetition of simulations did not lead to post-traumatic stress disorder.

trial registrationClinicalTrials.gov NCT02424890.

Indexed as

Activities of Daily LivingEmergency Medical ServicesSimulation TrainingAdultCircadian RhythmCritical CareDisease ProgressionFemaleHeart RateHumansMalePeriodicityRecurrenceRisk FactorsStress Disorders, Post-TraumaticStress, Psychological

Identifiers

PMID31344077
PMCPMC6657860
OpenAlexW2962975564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.