ArticlePloS one2019
Microbial community modulates growth of symbiotic fungus required for stingless bee metamorphosis.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Host-AdaptedMicroorganisms · 2026Article
- Beyond Standard Protocols: Advanced Patented Technology for Comprehensive Toxicity Assessments in Neotropical Bees.Toxics · 2026Article
- Distinct colony niches shape associated microbiotas in Neotropical stingless bees.Genetics and molecular biology · 2026Article
- Spatial segregation and cross-kingdom interactions drive stingless bee hive microbiome assembly.Nature communications · 2025Article
- On the Origins of Symbiotic Fungi in Carmine Cochineals and Their Function in the Digestion of Plant Polysaccharides.Insects · 2024Article
- Melipona stingless bees and honey microbiota reveal the diversity, composition, and modes of symbionts transmission.FEMS microbiology ecology · 2024Article
- Extracts ofMicroorganisms · 2023Article
- Bees just wanna have fungi: a review of bee associations with nonpathogenic fungi.FEMS microbiology ecology · 2023Review
- Temporal Changes in Gut Microbiota Composition and Pollen Diet Associated with Colony Weakness of a Stingless Bee.Microbial ecology · 2023Article
- Bacteria, yeasts, and fungi associated with larval food of Brazilian native stingless bees.Scientific reports · 2023Article
- Crude Extracts ofViruses · 2023Article
- Further evidences of an emerging stingless bee-yeast symbiosis.Frontiers in microbiology · 2023Article
- Fungivorous mites enhance the survivorship and development of stingless bees even when exposed to pesticides.Scientific reports · 2022Article
- Antimicrobial activity of supernatants produced by bacteria isolated from Brazilian stingless bee's larval food.BMC microbiology · 2022Article
- Diversity and antibacterial potential of the Actinobacteria associated withFrontiers in microbiology · 2022Article
- The composition of bacteria in gut and beebread of stingless bees (Apidae: Meliponini) from tropics Yunnan, China.Antonie van Leeuwenhoek · 2021Article
- Article
- Antioxidant-Based Medicinal Properties of Stingless Bee Products: Recent Progress and Future Directions.Biomolecules · 2020Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
The Brazilian stingless bee Scaptotrigona depilis requires the brood cells-associated fungus Zygosaccharomyces sp. as steroid source for metamorphosis. Besides the presence of Zygosaccharomyces sp., other fungi inhabit S. depilis brood cells, but their biological functions are unknown. Here we show that Candida sp. and Monascus ruber, isolated from cerumen of S. depilis brood provisions, interact with Zygosaccharomyces sp. and modulate its growth. Candida sp. produces volatile organic compounds (VOCs) that stimulate Zygosacchromyces sp. development. Monascus ruber inhibits Zygosacchromyces sp. growth by producing lovastatin, which blocks steroid biosynthesis. We also observed that in co-cultures M. ruber inhibits Candida sp. through the production of monascin. The modulation of Zygosaccharomyces sp. growth by brood cell-associated fungi suggests their involvement in S. depilis larval development. This tripartite fungal community opens new perspectives in the research of microbial interactions with bees.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.