ArticlePain medicine (Malden, Mass.)2020
Linking Persistent Pain and Frailty in Older Adults.
Article in Pain medicine (Malden, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review on the associations between low back pain and frailty in community-dwelling older adults.Chiropractic & manual therapies · 2025Pooled it
- Pain as an underrecognized geriatric syndrome in hospitalized older adults with major neurocognitive disorder: clinical correlates and outcomes.European geriatric medicine · 2026Observational
- Pain and frailty progression in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort study.The lancet. Healthy longevity · 2026Article
- Performance-Based and Self-Reported Frailty in Older Adults with or Without Fibromyalgia.European journal of investigation in health, psychology and education · 2026Article
- Labor intensity as an independent risk factor for frailty in older farmers: evidence from a multi-region survey in Guizhou, China.Frontiers in public health · 2026Article
- Association between frailty status and pain, balance, and quality of life in patients with lumbar spinal stenosis.Turkish journal of medical sciences · 2026Article
- Pain characteristics and incident frailty in community-dwelling older adults: dose-response relationships and sex differences in a longitudinal study on aging in Taiwan.Frontiers in public health · 2026Article
- Association between chronic pain severity, falls, frailty and perceived health in older adults at risk of falls.European journal of medical research · 2025Article
- A Bayesian Structural Equation Model to Predict Quality of Life in European Older Adults.European journal of investigation in health, psychology and education · 2025Article
- Longitudinal association between frailty and pain in three prospective cohorts of older population.The journal of nutrition, health & aging · 2025Article
- Temporal association between chronic pain and frailty occurrence, and the modifiable role of a healthy lifestyle in Chinese middle-aged and older population: a community based, prospective cohort study.Aging clinical and experimental research · 2025Article
- Pain and Frailty in Childhood Cancer Survivors: A Narrative Review.Current oncology (Toronto, Ont.) · 2024Review
- Frailty as a mediator of postoperative delirium in older adults undergoing orthopedic surgery: A causal mediation analysis.International journal of nursing studies advances · 2024Article
- Associations among frailty conditions and pain indicators: Data from 22 356 European older adults.Geriatrics & gerontology international · 2024Observational
- Multimorbidity and COVID-19 Outcomes in the Emergency Department: Is the Association Mediated by the Severity of the Condition at Admission?Journal of clinical medicine · 2024Article
- What Predicts a Longer Period of Pain in Patients Referred to an Interdisciplinary Center for Pain Care?International journal of environmental research and public health · 2024Article
- [Interdisciplinary pain therapy in the elderly].Schmerz (Berlin, Germany) · 2024Review
- The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping.Drugs & aging · 2024Article
- Mapping review of pain management programmes and psychological therapies for community-dwelling older people living with pain.European geriatric medicine · 2024Review
- The vicious cycle of frailty and pain: a two-sided causal relationship revealed.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectiveIn older adults, the impact of persistent pain goes beyond simple discomfort, often contributing to worsening functional outcomes and ultimately frailty. Frailty is a geriatric syndrome that, like persistent pain, increases in prevalence with age and is characterized by a decreased ability to adapt to common stressors such as acute illness, thereby increasing risk for multiple adverse health outcomes. Evidence supports a relationship between persistent pain and both the incidence and progression of frailty, independent of health, social, and lifestyle confounders. DESIGN AND
settingIn this article, we synthesize recent evidence linking persistent pain and frailty in an effort to clarify the nature of the relationship between these two commonly occurring geriatric syndromes.
settingWe propose an integration of the frailty phenotype model by considering the impact of persistent pain on vulnerability toward external stressors, which can ultimately contribute to frailty in older adults. RESULTS AND
conclusionsIncorporating persistent pain into the frailty construct can help us better understand frailty and ultimately improve care for patients with, as well as those at increased risk for, pain and frailty.
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