Evidence map›Paper›PMID 31343576›Full record

ArticleTransplantation2020

Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey.

Mara A McAdams-DeMarco, Sarah E Van Pilsum Rasmussen, Nadia M Chu, Dayawa Agoons, Ronald F Parsons, Tarek Alhamad, Kirsten L Johansen, Stefan G Tullius, Raymond Lynch, Meera N Harhay and 13 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Visceral Fat Obesity Correlates with Frailty in Middle-Aged and Older Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Trial
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Practices in the management of kidney transplant candidates and recipients with obesity: A survey of United States transplant programs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  17. Article
  18. Frailty and Prehabilitation: Navigating the Road to a Successful Transplant.Journal of the American Society of Nephrology : JASN · 2024
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 1 country.

Mara A McAdams-DeMarcoDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Sarah E Van Pilsum RasmussenDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Nadia M ChuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Dayawa AgoonsDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Ronald F ParsonsDepartment of Surgery, Emory University School of Medicine, Atlanta, GA.
Tarek AlhamadDivision of Nephrology, Washington University in St. Louis, St. Louis, MO.
Kirsten L JohansenDivision of Nephrology, Hennepin County Medical Center, Minneapolis, MN.
Stefan G TulliusDepartment of Surgery, Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Raymond LynchDepartment of Surgery, Emory University School of Medicine, Atlanta, GA.
Meera N HarhayDepartment of Medicine, Division of Nephrology, Drexel University College of Medicine, Philadelphia, PA.
Maya K RaoDivision of Nephrology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Joseph BergerDivision of Nephrology, University of Texas Southwestern Medical School, Dallas, TX.
Matthew CooperDepartment of Surgery, Georgetown University School of Medicine, Washington, DC.
Jane C TanDepartment of Medicine, Division of Nephrology, Stanford University, Stanford, CA.
XingXing S ChengDepartment of Medicine, Division of Nephrology, Stanford University, Stanford, CA.
Kenneth J WoodsideDepartment of Surgery, Medical School, University of Michigan, Ann Arbor, MI.
Sandesh ParajuliDepartment of Medicine, Division of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Krista L LentineCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO.
Bruce KaplanBaylor Scott and White Health, Temple, TX.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jon A KobashigawaComprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Darshana DadhaniaDivision of Nephrology and Hypertension, Weill Cornell Medicine, New York, NY.
AST Kidney Pancreas Community of Practice Workgroup
Johns Hopkins Medicine · USEmory University · USStanford University · USBaylor Scott & White Health · USCedars-Sinai Medical Center · USCornell University · USDrexel University · USGeorgetown University · USHennepin County Medical Center · USJohns Hopkins University · USSaint Louis University · USUniversity of Wisconsin–Madison · USWashington University in St. Louis · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Kidney transplantation in older, frail and cognitively impaired adults with ESRD: Balancing utility vs. justiceR01AG055781 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2017 to 2021
$4.2M
Frailty and Risk Prediction in Older Adults Considering Kidney Transplantation Supp OlorundareR01AG042504 · NIA · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2013 to 2017
$3.4M
Consequences of Aging on Immune Response and Transplant OutcomeR01AG039449 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI TULLIUS, STEFAN GUNTHER · 2012 to 2016
$1.6M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Patterns and Implications of Functional Decline Among Kidney Transplant CandidatesK23DK105207 · NIDDK · DREXEL UNIVERSITY · PI HARHAY, MEERA NAIR · 2015 to 2019
$861k
Consequences of Aging on Immune Response and Transplant OutcomeR56AG039449 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI TULLIUS, STEFAN GUNTHER · 2018 to 2018
$643k
Frailty and Adverse Health Outcomes of Aging in Older Adults with Kidney FailureK01AG043501 · NIA · JOHNS HOPKINS UNIVERSITY · PI MCADAMS DEMARCO, MARA A. · 2014 to 2018
$624k
A pilot randomized trial of arteriovenous fistula versus arteriovenous graft in elderly patients with advanced kidney diseaseR03AG053294 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RAO, MAYA K · 2016 to 2017
$240k
NIAID NIH HHS K24 AI144954NIA NIH HHS K01 AG043501NIA NIH HHS P30 AG021334NIA NIH HHS R01 AG039449NIA NIH HHS R01 AG042504NIA NIH HHS R01 AG055781NIA NIH HHS R03 AG053294NIA NIH HHS R56 AG039449NIDDK NIH HHS K23 DK105207NIDDK NIH HHS K24 DK101828
6 · The paper itself

Abstract

backgroundGiven the potential utility of frailty, a clinical phenotype of decreased physiologic reserve and resistance to stressors, to predict postkidney transplant (KT) outcomes, we sought to understand the perceptions and practices regarding frailty measurement in US KT programs.

methodsSurveys were emailed to American Society of Transplantation Kidney/Pancreas Community of Practice members and 202 US transplant programs (November 2017 to April 2018). Program characteristics were gleaned from Scientific Registry of Transplant Recipients.

resultsThe 133 responding programs (response rate = 66%) represented 77% of adult KTs and 79% of adult KT candidates in the United States. Respondents considered frailty to be a useful concept in evaluating candidacy (99%) and endorsed a need to develop a frailty measurement specific to KT (92%). Frailty measurement was more common during candidacy evaluation (69%) than during KT admission (28%). Of the 202 programs, 38% performed frailty assessments in all candidates while 23% performed assessments only for older candidates. There was heterogeneity in the frailty assessment method; 18 different tools were utilized to measure frailty. The most common tool was a timed walk test (19%); 67% reported performing >1 tool. Among programs that measure frailty, 53% reported being less likely to list frail patients for KT.

conclusionsAmong US KT programs, frailty is recognized as a clinically relevant construct and is commonly measured at evaluation. However, there is considerable heterogeneity in the tools used to measure frailty. Efforts to identify optimal measurement of frailty using either an existing or a novel tool and subsequent standardization of its measurement and application across KT programs should be considered.

Indexed as

RegistriesSocieties, MedicalTransplant RecipientsAgedFemaleFrailtyHumansIncidenceKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPostoperative ComplicationsProspective StudiesRisk FactorsUnited States

Identifiers

PMID31343576
PMCPMC6834867
OpenAlexW2962953017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.