Evidence map›Paper›PMID 31342907›Full record

Trial reportJournal of medical Internet research2019

A Web-Based Exercise System (e-CuidateChemo) to Counter the Side Effects of Chemotherapy in Patients With Breast Cancer: Randomized Controlled Trial.

Angelica Ariza-Garcia, Mario Lozano-Lozano, Noelia Galiano-Castillo, Paula Postigo-Martin, Manuel Arroyo-Morales, Irene Cantarero-Villanueva

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02350582 nacompletednot on this map

e-CUIDACHEMO: Telerehabilitation During Chemotherapy in Breast Cancer Patients

TypeinterventionalSponsorUniversidad de GranadaRan2012 to 2016Enrolled60ConditionsBreast CancerArmsTelerehabilitation eCUIDATE system
NCT04826367 nacompletednot on this mapstarted 2021, after this paper: background citation

Relaxation Training By Tele-Rehabilitation Program In Patients With Breast Cancer Receiving Chemotherapy During COVID-19.

TypeinterventionalSponsorHacettepe UniversityRan2021 to 2022Enrolled69ConditionsBreast CancerArmsTelerehabilitation-based relaxation exercise group (EG)
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Six-Minute Walk Distance in Breast Cancer Survivors-A Systematic Review with Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  9. The impact of multimodal high intensity exercise program comparing online and onsite interventions in breast cancer survivors: a randomized controlled trial.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Trial
  10. Trial
  11. The role of digital rehabilitation therapy in enhancing upper limb function recovery following surgery in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Cardio-oncology rehabilitation: are we ready?European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Angelica Ariza-Garcia *Department of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0003-1982-9997
Mario Lozano-Lozano *Department of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0001-5854-3567
Noelia Galiano-Castillo *Department of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0002-6825-4213
Paula Postigo-MartinDepartment of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0001-6430-5207
Manuel Arroyo-MoralesDepartment of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0003-3552-8051
Irene Cantarero-VillanuevaDepartment of Physical Therapy, University of Granada, Granada, Spain.ORCID 0000-0002-3834-1711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer patients have to face a high-risk state during chemotherapy, which involves deterioration of their health including extensive physical deterioration. Face-to-face physical exercise programs have presented low adherence rates during medical treatment, and telehealth systems could improve these adherence rates.

objectiveThis study aimed to evaluate the effectiveness of a Web-based exercise program (e-CuidateChemo) to mitigate the side effects of chemotherapy on the physical being, anthropometric aspects, and body composition.

methodsA total of 68 patients diagnosed with breast cancer, who were undergoing chemotherapy, were enrolled. The patients were categorized into two groups: e-CuidateChemo (n=34) and controls (n=34). The e-CuidateChemo group participated in an adapted 8-week tailored exercise program through a Web-based system. A blinded, trained researcher assessed functional capacity, strength, anthropometric parameters, and body composition. The intervention effects were tested using analysis of covariance and Cohen d tests.

resultsFunctional capacity improved significantly in the e-CuidateChemo group compared to the control group (6-minute walk test: 62.07 [SD 130.09] m versus -26.34 [SD 82.21] m; 6-minute walk test % distance predicted: 10.81% [SD 22.69%] m versus -4.60% [SD 14.58%]; between-group effect: P=.015 for both). The intervention group also showed significantly improved secondary outcomes such as between-group effects for abdominal (24.93 [SD 26.83] s vs -18.59 [SD 38.69] s), back (12.45 [SD 10.20] kg vs 1.39 [10.72] kg), and lower body (-2.82 [SD 3.75] s vs 1.26 [SD 2.84] s) strength; all P<.001 compared to the control group.

conclusionsThis paper showed that a Web-based exercise program was effective in reversing the detriment in functional capacity and strength due to chemotherapy.

trial registrationClinicalTrials.gov NCT02350582; https://clinicaltrials.gov/ct2/show/NCT02350582.

Indexed as

Breast NeoplasmsExerciseExercise TherapyFemaleHumansInternetMiddle AgedTelemedicinebreast cancerchemotherapye-healthphysical fitnessrandomized control trialtelehealththerapeutic exercise

Identifiers

PMID31342907
PMCPMC6685131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.