Evidence map›Paper›PMID 31342906›Full record

ArticleJMIR mHealth and uHealth2019

Electronic Patient-Reported Outcome Measures in Radiation Oncology: Initial Experience After Workflow Implementation.

Franziska Hauth, Verena Bizu, Rehan App, Heinrich Lautenbacher, Alina Tenev, Michael Bitzer, Nisar Peter Malek, Daniel Zips, Cihan Gani

Open access · goldAbstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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  2. Mobile applications in radiation oncology-current choices and future potentials.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
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  12. Oncologic treatment support via a dedicated mobile app: a prospective feasibility evaluation (OPTIMISE-1).Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Franziska HauthUniversity Hospital Tübingen, Department of Radiation Oncology, Tübingen, Germany.ORCID 0000-0002-2432-7716
Verena BizuUniversity Hospital Tübingen, Section for Information Technology, Tübingen, Germany.ORCID 0000-0003-4305-1054
Rehan AppUniversity Hospital Tübingen, Section for Information Technology, Tübingen, Germany.ORCID 0000-0003-4601-2368
Heinrich LautenbacherUniversity Hospital Tübingen, Section for Information Technology, Tübingen, Germany.ORCID 0000-0002-6676-1545
Alina TenevUniversity Hospital Tübingen, Department of Radiation Oncology, Tübingen, Germany.ORCID 0000-0002-9744-7284
Michael BitzerUniversity Hospital Tübingen, Internal Medicine I, Tübingen, Germany.ORCID 0000-0002-4463-8263
Nisar Peter MalekUniversity Hospital Tübingen, Internal Medicine I, Tübingen, Germany.ORCID 0000-0002-9916-4608
Daniel ZipsUniversity Hospital Tübingen, Department of Radiation Oncology, Tübingen, Germany.ORCID 0000-0001-5779-9675
Cihan GaniUniversity Hospital Tübingen, Department of Radiation Oncology, Tübingen, Germany.ORCID 0000-0003-0242-9428
University Children's Hospital Tübingen · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMobile health (mHealth) technologies are increasingly used in various medical fields. However, the potential of mHealth to improve patient care in radiotherapy by acquiring electronic patient reported outcome measures (ePROMs) during treatment has been poorly studied so far.

objectiveThe aim of this study was to develop and implement a novel Web app (PROMetheus) for patients undergoing radiotherapy. Herein, we have reported our experience with a focus on feasibility, patient acceptance, and a correlation of ePROMs with the clinical course of the patients.

methodsIn the period between January and June 2018, 21 patients used PROMetheus to score side effects, symptoms, and quality of life-related parameters during and after their treatment. Items of the Patient Reported Outcome version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) were chosen based on the primary site of disease, 27 items for head and neck tumors, 21 items for thoracic tumors, and 24 items for pelvic tumors.

resultsIn total, 17 out of the 21 patients (81%) regularly submitted ePROMs and more than 2500 data points were acquired. An average of 5.2, 3.5, and 3.3 min was required to complete the head and neck, thorax, and pelvis questionnaires, respectively. ePROMS were able to detect the occurrence of both expected and unexpected side effects during the treatment. In addition, a gradual increase in the severity of side effects over the course the treatment and their remission afterward could be observed with ePROMs. In total, 9 out of the 17 patients (53%), mostly those with head and neck and thoracic cancers, reported PRO-CTCAE grade III or IV fatigue with severe impairments of activities of daily life.

conclusionsThis study shows the successful implementation of an ePROM system and a high patient acceptance. ePROMs have a great potential to improve patient care in radiotherapy by providing a comprehensive documentation of symptoms and side effects, especially of ones that are otherwise underreported.

Indexed as

Activities of Daily LivingAgedBig DataElectronic Data ProcessingFatigueFeasibility StudiesFemaleHead and Neck NeoplasmsHumansImplementation ScienceMaleMiddle AgedNeoplasm StagingPatient Acceptance of Health CarePatient Reported Outcome MeasuresPelvic NeoplasmseHealthmHealthpatient reported outcome measuresradiation oncology

Identifiers

PMID31342906
PMCPMC6685133
OpenAlexW2933627874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.