Evidence map›Paper›PMID 31342832›Full record

Observational studyJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Within-lesion heterogeneity of subcortical DWI lesion evolution, and stroke outcome: A voxel-based analysis.

Marco Duering, Ruth Adam, Frank A Wollenweber, Anna Bayer-Karpinska, Ebru Baykara, Leidy Y Cubillos-Pinilla, Benno Gesierich, Miguel Á Araque Caballero, Sophia Stoecklein, Michael Ewers and 2 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01334749 (Determinants of Dementia After Stroke), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01334749 active not recruitingnot on this map

Determinants of Dementia After Stroke

TypeobservationalSponsorLudwig-Maximilians - University of MunichRan2011 to 2029Enrolled736ConditionsIschemic Stroke, Hemorrhagic Stroke
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Assessing cortical cerebral microinfarcts on iron-sensitive MRI in cerebral small vessel disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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  7. Heart-brain mapping: Cardiac atrial function is associated with distinct cerebral regions with high free water in older adults.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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  12. Lenticulostriate artery combined with neuroimaging markers of cerebral small vessel disease differentiate the pathogenesis of recent subcortical infarction.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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  13. Venous disruption affects white matter integrity through increased interstitial fluid in cerebral small vessel disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marco DueringInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Ruth AdamInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Frank A WollenweberInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Anna Bayer-KarpinskaInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Ebru BaykaraInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Leidy Y Cubillos-PinillaInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0003-1535-8366
Benno GesierichInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Miguel Á Araque CaballeroInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Sophia StoeckleinDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Michael EwersInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Ofer PasternakDepartments of Psychiatry and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Martin DichgansInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

The fate of subcortical diffusion-weighted imaging (DWI) lesions in stroke patients is highly variable, ranging from complete tissue loss to no visible lesion on follow-up. Little is known about within-lesion heterogeneity and its relevance for stroke outcome. Patients with subcortical stroke and recruited through the prospective DEDEMAS study (NCT01334749) were examined at baseline (

Indexed as

Recovery of FunctionAgedAged, 80 and overDiffusion Magnetic Resonance ImagingFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedNeuroimagingStrokeClinical outcomediffusion tensor imagingfree waterstrokesubcortical infarction

Identifiers

PMID31342832
PMCPMC7308518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.