Evidence map›Paper›PMID 31342665›Full record

ArticleBrain and behavior2019

Acute disseminated encephalomyelitis following varicella-zoster virus infection: Case report of effective treated both in clinical symptom and neuroimaging.

Qi Wang, Li-Na Cai, Xiang-Qing Wang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Qi WangDepartment of Neurology, Aerospace Center Hospital, Beijing, China.
Li-Na CaiDepartment of Neurology, Aerospace Center Hospital, Beijing, China.
Xiang-Qing WangDepartment of Neurology, Chinese People's Liberation Army General Hospital, Beijing, China.ORCID 0000-0003-2555-466X
Aerospace Center Hospital · CNChinese General Hospital College of Nursing and Liberal Arts · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute disseminated encephalomyelitis (ADEM) is an idiopathic inflammatory demyelinating disorder of the central nervous system (CNS). Early treatment is the key for neurological recovery.

methodsA case of ADEM associated with varicella-zoster virus infection was presented, in which magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) examinations were included.

resultsMagnetic resonance imaging of the brain revealed multiple hyperintense lesions at the subcortical level on fluid-attenuated inversion recovery (FLAIR), and MRI of the spinal cord revealed longitudinally segmented hyperintense lesions at the spinal cord on T2-weighted images. The patient was treated with methylprednisolone and gancyclovir, and had a favorable recovery. Subsequent MRI of the brain and cervical cord showed the previous abnormal hyperintensities had markedly disappeared.

conclusionA rare case of ADEM with longitudinal segmented hyperintense lesions at the spinal cord on T2-weighted images was presented. Excellent response to ADEM treatment with high-dose steroids was reported resulting in a remarkable neurological recovery. A long-term follow-up is needed for prognosis.

Indexed as

AdolescentAnti-Inflammatory AgentsAntiviral AgentsBrainEncephalomyelitis, Acute DisseminatedFemaleGanciclovirHumansMagnetic Resonance ImagingMethylprednisoloneNeuroimagingSpinal CordTreatment OutcomeVaricella Zoster Virus InfectionAnti-Inflammatory AgentsAntiviral AgentsGanciclovirMethylprednisoloneacute disseminated encephalomyelitiscentral nervous systemmultiple sclerosisneuroimaging

Identifiers

PMID31342665
PMCPMC6749488
OpenAlexW2963968855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.