ArticleJournal of child psychology and psychiatry, and allied disciplines2019
Childhood maltreatment, neuropsychological function and suicidal behavior.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 45 citations in OpenAlex.
- Explaining the Link Between PTSD and Suicide: A Meta-Analysis to Introduce the CEASE Framework.Psychological reports · 2026Article
- Childhood Maltreatment, Executive Function, and Suicide Attempts in Adolescents.Child maltreatment · 2024Article
- Proinflammatory cytokine levels, cognitive function, and suicidal symptoms of adolescents and young adults with major depressive disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Psycho-social sufferings and sexual difficulties among female survivors of child sexual abuse in Pakistan.BMC psychiatry · 2024Article
- Impact of childhood maltreatment on aging: a comprehensive Mendelian randomization analysis of multiple age-related biomarkers.Clinical epigenetics · 2024Article
- Psychological Resilience Mediates the Association Between Childhood Maltreatment and Self-Harm Phenotype in Chinese Early Adolescents.Child psychiatry and human development · 2024Article
- Theta oscillatory dynamics serving cognitive control index psychosocial distress in youth.Neurobiology of stress · 2024Article
- Clinical and Neuropsychological Features of Suicide Attempters in Tehran, Iran: A Comparative Study.Medical journal of the Islamic Republic of Iran · 2024Article
- Neurocognitive and clinical characteristics of elementary school-aged children with a history of suicidal thoughts and behaviors.Journal of affective disorders · 2023Article
- Child maltreatment and youth suicide risk: A developmental conceptual model and implications for suicide prevention.Development and psychopathology · 2023Article
- Issues and opportunities of digital phenotyping: ecological momentary assessment and behavioral sensing in protecting the young from suicide.Frontiers in psychology · 2023Article
- Exploring the relationship between suicide vulnerability, impulsivity and executive functioning during COVID-19: A longitudinal analysis.Psychiatry research communications · 2022Article
- Cognitive Flexibility and Impulsivity Deficits in Suicidal Adolescents.Research on child and adolescent psychopathology · 2022Article
- Direct and Indirect Effects of Child Maltreatment on Suicidal Ideation among Chinese Left-Behind Children: Does Gender Make a Difference?Behavioral sciences (Basel, Switzerland) · 2022Article
- Effect of frequency of parent to child maltreatment on symptoms of anxiety disorder in Pakistani adolescents: A community based cohort study.Child abuse & neglect · 2022Article
- Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study.Brain sciences · 2022Article
- Characteristics and Mediating Effect of Gut Microbiota With Experience of Childhood Maltreatment in Major Depressive Disorder.Frontiers in neuroscience · 2022Article
- Risk factors for pre-adolescent onset suicidal behavior in a high-risk sample of youth.Journal of affective disorders · 2021Article
- Association between family history of suicide attempt and neurocognitive functioning in community youth.Journal of child psychology and psychiatry, and allied disciplines · 2021Article
- Influence of the GABA Receptor Subunit Gene Polymorphism and Childhood Sexual Abuse on Processing Speed in Major Depression and Suicide Attempt.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSuicide is the second leading cause of death in young people. Childhood maltreatment, neuropsychological dysfunction and psychopathology have each been shown to increase risk for suicidal behavior. However, few studies have examined their interactions and the effects of those interactions on suicidal behavior.
methodsAcross two sites, a total of 382 offspring of depressed parents underwent neuropsychological assessments. This high-risk sample included nearly equal numbers of males and females. Average age at the time of neuropsychological assessment was 18.5 years. The most prevalent lifetime psychiatric disorders were mood (43%), anxiety (37%) and alcohol and substance use disorders (21%). Childhood maltreatment was reported by 44% of offspring. Participants underwent extensive neuropsychological testing assessing the following domains: attention, memory, executive function, working memory, language fluency, and impulse control. Logistic regression was used to examine the association of reported childhood maltreatment, neuropsychological functioning, psychopathology and their interactions with suicidal behavior. Bonferroni correction was used to adjust for multiple comparisons.
resultsMaltreatment was associated with increased risk of suicidal behavior with odds ratios ranging between 2.40 and 4.43. Moderation analyses found that adaptive neuropsychological functioning was not protective against childhood maltreatment's effect on suicidal risk. While lifetime history of mood disorder was strongly associated with suicidal behavior, higher scores in working memory (OR = 0.21; 95% CI = 0.09, 0.45; p < .001) and executive function (OR = 0.15; 95% CI = 0.05, 0.43; p < .001) were protective against suicidal behavior even in the presence of a lifetime history of mood disorder.
conclusionsFurther research is needed to determine how neuropsychological capacity protects depressed patients against the risk of suicidal behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.