Evidence map›Paper›PMID 31342337›Full record

ArticleAnnals of biomedical engineering2020

A Concentric Tube Robot System for Rigid Bronchoscopy: A Feasibility Study on Central Airway Obstruction Removal.

Joshua B Gafford, Scott Webster, Neal Dillon, Evan Blum, Richard Hendrick, Fabien Maldonado, Erin A Gillaspie, Otis B Rickman, S Duke Herrell, Robert J Webster

Open access · greenAbstract read
In one paragraph

Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Perseus: perception with semantic endoscopic understanding and SLAM.International journal of computer assisted radiology and surgery · 2026
    Article
  3. Few-Shot Physics-Informed Neural Network for Shape Reconstruction of Concentric-Tube Robots.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2026
    Article
  4. Article
  5. Article
  6. The utility of a rigid bronchoscope.Breathe (Sheffield, England) · 2025
    Review
  7. Article
  8. Article
  9. A Model to Predict Deflection of an Active Tendon-Driven Notched Needle Inside Soft Tissue.Journal of engineering and science in medical diagnostics and therapy · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. A Millimeter-Scale Soft Robot for Tissue Biopsy Procedures.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Design of a multi-arm concentric-tube robot system for transnasal surgery.Medical & biological engineering & computing · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joshua B GaffordMechanical Engineering Department, Vanderbilt University, Nashville, TN, USA. joshua.b.gafford@vanderbilt.edu.ORCID http://orcid.org/0000-0002-5955-5831
Scott WebsterVirtuoso Surgical, Inc., Nashville, TN, USA.
Neal DillonVirtuoso Surgical, Inc., Nashville, TN, USA.
Evan BlumVirtuoso Surgical, Inc., Nashville, TN, USA.
Richard HendrickVirtuoso Surgical, Inc., Nashville, TN, USA.
Fabien MaldonadoMechanical Engineering Department, Vanderbilt University, Nashville, TN, USA.
Erin A GillaspieVanderbilt University Medical Center, Nashville, TN, USA.
Otis B RickmanVanderbilt University Medical Center, Nashville, TN, USA.
S Duke HerrellMechanical Engineering Department, Vanderbilt University, Nashville, TN, USA.
Robert J WebsterMechanical Engineering Department, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · USVanderbilt Health · US

Funding

Reopening the Central Airway With Needle-Size Tentacle ManipulatorsR44HL140709 · NHLBI · VIRTUOSO SURGICAL, INC. · PI HENDRICK, RICHARD JOSEPH · 2019 to 2020
$1.6M
Reopening the Central Airway With Needle-Size Tentacle ManipulatorsR41HL140709 · NHLBI · VIRTUOSO SURGICAL, INC. · PI WEBSTER, ROBERT JAMES · 2018 to 2018
$225k
NHLBI NIH HHS R41 HL140709NHLBI NIH HHS R44 HL140709NIH HHS R41 HL140709
6 · The paper itself

Abstract

New robotic systems have recently emerged to assist with peripheral lung access, but a robotic system for rigid bronchoscopy has yet to be developed. We describe a new robotic system that can deliver thin robotic manipulators through the ports of standard rigid bronchoscopes. The manipulators bend and elongate to provide maneuverability of surgical tools at the endoscope tip, without endoscope motion. We describe an initial feasibility study on the use of this system to bronchoscopically treat a central airway obstruction (CAO). CAO is prevalent and can be life-threatening in patients with large tumors, and conventional rigid bronchoscopic treatments place patients at risk of complications including broken teeth, neck trauma and damage to oropharyngeal structures due to significant forces induced by bronchoscope tilting and manipulation. In this study, we used an ex vivo ovine airway model to demonstrate the ability of a physician using the robotic system to efficiently remove tissue and restore the airway. Pre- and post-operative CT scans showed that the robot was able to reduce the degree of airway obstruction stenosis from 75 to 14% on average for five CAO resections performed in an ex vivo animal model. Using cadaver experiments, we demonstrated the potential of the robotic system to substantially reduce the intraoperative forces applied to the patient's head and neck (from 80.6 to 4.1 N). These preliminary results illustrate that CAO removal is feasible with our new rigid bronchoscopy robot system, and that this approach has the potential to reduce forces applied to the patient due to bronchoscope angulation, and thereby reduce the risk of complications encountered during CAO surgery.

Indexed as

RoboticsAirway ObstructionAnimalsBronchoscopyCadaverFeasibility StudiesSheepBronchoscopyCentral Airway ObstructionRobotics

Identifiers

PMID31342337
PMCPMC6930337
OpenAlexW2963068794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.