Evidence map›Paper›PMID 31342224›Full record

ArticleJournal of industrial microbiology & biotechnology2019

Rational development of transformation in Clostridium thermocellum ATCC 27405 via complete methylome analysis and evasion of native restriction-modification systems.

Lauren A Riley, Lexiang Ji, Robert J Schmitz, Janet Westpheling, Adam M Guss

Open access · hybridAbstract read
In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. EngineeringMetabolic engineering communications · 2026
    Article
  3. Article
  4. EngineeringbioRxiv : the preprint server for biology · 2025
    Article
  5. Improving the Transformation Efficiency ofACS synthetic biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Discovering methylated DNA motifs in bacterial nanopore sequencing data with MIJAMP.Journal of industrial microbiology & biotechnology · 2024
    Article
  10. Application of functional genomics for domestication of novel non-model microbes.Journal of industrial microbiology & biotechnology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. A Single Nucleotide Change in theApplied and environmental microbiology · 2022
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lauren A RileyBredesen Center, University of Tennessee, Knoxville, TN, 37996, USA.
Lexiang JiInstitute of Bioinformatics, University of Georgia, Athens, GA, 30602, USA.
Robert J SchmitzDepartment of Genetics, University of Georgia, Athens, GA, 30602, USA.
Janet WestphelingDepartment of Genetics, University of Georgia, Athens, GA, 30602, USA.
Adam M GussBredesen Center, University of Tennessee, Knoxville, TN, 37996, USA. gussam@ornl.gov.ORCID http://orcid.org/0000-0001-5823-5329
University of Georgia · USOak Ridge National Laboratory · USUniversity of Tennessee at Knoxville · US

Funding

Biological and Environmental Research BioEnergy Science CenterBiological and Environmental Research Center for Bioenergy Innovation
6 · The paper itself

Abstract

A major barrier to both metabolic engineering and fundamental biological studies is the lack of genetic tools in most microorganisms. One example is Clostridium thermocellum ATCC 27405

Indexed as

EpigenomeAcetivibrio thermocellusDNA MethylationDNA Restriction-Modification EnzymesEscherichia coliMetabolic EngineeringPlasmidsDNA Restriction-Modification EnzymesClostridium thermocellumMethylomeReal-time sequencingRestriction–modification systemsSingle moleculeWhole-genome bisulfite sequencing

Identifiers

PMID31342224
PMCPMC6791906
OpenAlexW2962722055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.