ArticleCurrent infectious disease reports2019
Clinical Decision Support Systems and Their Role in Antibiotic Stewardship: a Systematic Review.
Article in Current infectious disease reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Strategies and outcomes of CDSS implementation for antimicrobial stewardship in hospital settings: a systematic review.Antimicrobial resistance and infection control · 2026Pooled it
- The effects of information technology interventions for optimizing antibiotic prescribing in urinary tract infections: a systematic review.BMC infectious diseases · 2025Pooled it
- Pooled it
- Factors influencing the implementation of decision support systems for antibiotic prescription in hospitals: a systematic review.BMC medical informatics and decision making · 2023Pooled it
- Linking antimicrobial resistance surveillance to antibiotic policy in healthcare settings: the COMBACTE-Magnet EPI-Net COACH project.The Journal of antimicrobial chemotherapy · 2020Pooled it
- Use of stewardship smartphone applications by physicians and prescribing of antimicrobials in hospitals: A systematic review.PloS one · 2020Pooled it
- A clinical decision support system improves antibiotic therapy for upper urinary tract infection in a randomized single-blinded study.BMC health services research · 2020Trial
- The GUIDE-CDSS framework: a comprehensive framework to GUIDE and evaluate the implementation of Clinical Decision Support Systems in healthcare, based on an overview of reviews.Journal of the American Medical Informatics Association : JAMIA · 2026Review
- Optimizing antimicrobial stewardship in urology: a qualitative study on needs, values and requirements for clinical decision support.Infection prevention in practice · 2026Article
- [Antibiotic use: psychological factors influencing perceptions and behavior of physicians and patients].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026Review
- Enhancing Continuous Medication Safety Through e-Prescription and Clinical Decision Support Systems in Outpatient Practices and Pharmacies: Protocol for a Multiperspective Study (eRIKA Study).JMIR research protocols · 2026Article
- Cross-sectional survey to assess the status of antimicrobial stewardship programs in public Chilean hospitals.Antimicrobial resistance and infection control · 2026Article
- Performance of predictive AI-based clinical decision support systems across clinical domains: A systematic review and meta-analysis.PLOS digital health · 2026Article
- Clinical Decision Support for Antibiotic Prescribing Duration in Children With Acute Otitis Media.JAMA network open · 2026Article
- Antimicrobial stewardship from a One Health perspective.Nature reviews. Microbiology · 2026Review
- Supervised Machine Learning to Identify Hospital Inpatients Needing a Change of Antibiotic Therapy in Real Time: Preclinical Diagnostic Evaluation and Feasibility Study.Open forum infectious diseases · 2026Article
- Optimization of Postoperative Antimicrobial Therapy in Surgical Patients Using a Clinical Decision Support System: Use Patterns and Clinical Outcomes.Medicina (Kaunas, Lithuania) · 2025Article
- Outpatient antibiotic prescribing by general dentists in the United States from 2018 through 2022.Journal of the American Dental Association (1939) · 2025Article
- An AI-Based Clinical Decision Support System for Antibiotic Therapy in Sepsis (KINBIOTICS): Use Case Analysis.JMIR human factors · 2025Article
- Healing soles: a microbiology-driven electronic health record-algorithm and order set to decrease antipseudomonal use in diabetic foot infections, a retrospective, observational, quasi-experimental study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThe purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT
findingsCDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardship. There are various types of CDSS implementations, both active and passive (provider initiated). Passive interventions were associated with more significant outcomes; however, both interventions appeared effective. In the reviewed literature, CDSSs were consistently associated with decreasing antibiotic consumption and narrowing the spectrum of antibiotic usage. Generally, guideline adherence was improved with CDSS, although this was not universal. The effect on other outcomes, such as mortality, Clostridiodes difficile infections, length of stay, and cost, inconsistently showed a significant difference. Overall, CDDS implementation has effectively decreased antibiotic consumption and improved guideline adherence across the various types of CDSS. Other positive outcomes were noted in certain settings, but were not universal. When creating a new intervention, it is important to identify the optimal structure and deployment of a CDSS for a specific setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.