Evidence map›Paper›PMID 31342119›Full record

ReviewCellular and molecular life sciences : CMLS2019

Review: immunoassays in DNA damage and instability detection.

Karolina Boguszewska, Michał Szewczuk, Sandra Urbaniak, Bolesław T Karwowski

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. ELISA for Detection of Total IgG Against YF 17DD.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karolina BoguszewskaDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151, Lodz, Poland. karolina.boguszewska@stud.umed.lodz.pl.ORCID http://orcid.org/0000-0003-3772-8540
Michał SzewczukDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151, Lodz, Poland.ORCID http://orcid.org/0000-0002-5680-6594
Sandra UrbaniakDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151, Lodz, Poland.ORCID http://orcid.org/0000-0003-1159-7167
Bolesław T KarwowskiDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151, Lodz, Poland. boleslaw.karwowski@umed.lodz.pl.ORCID http://orcid.org/0000-0001-6922-7834
Medical University of Lodz · PLUniversity of Łódź · PL

Funding

Narodowe Centrum Nauki 2016/23/B/NZ7/03367Uniwersytet Medyczny w Lodzi 503/3-045-02/503-31-002
6 · The paper itself

Abstract

The review includes information on the current state of knowledge of immunometric methods with emphasis on the possibility of deoxyribonucleic acid (DNA) damage detection. Beginning with basic immunoassay enzyme-linked immunosorbent assay (ELISA), this review describes methods such as tyramide signal amplification (TSA), enhanced polymer one-step staining (EPOS), and time resolved amplified cryptate emission (TRACE) as improvements of ELISA's developed over time to obtain more accurate results. In the second part of the review, surface plasmon resonance (SPR) and quantum dots (QDs) are presented as the newest outlooks in the context of immunoanalysis of biological material and molecular studies. The aim of this review is to briefly present immunoassays with emphasis on DNA damage detection; therefore, the types of methods are listed and described, types of signal indicators, basic definitions such as antigen and antibody are given. Every method is considered with an exemplary application focusing on DNA studies, DNA damage and instability detection.

Indexed as

DNA DamageDNAEnzyme-Linked Immunosorbent AssayImmunoassayOrganometallic CompoundsQuantum DotsSurface Plasmon ResonanceTyramineDNAeuropium(III) trisbipyridine cryptateOrganometallic CompoundsTyramineDNA damageImmunoassayQuantum dots (QDs)Surface plasmon resonance (SPR)Time resolved amplified cryptate emission (TRACE)Tyramide signal amplification (TSA)

Identifiers

PMID31342119
PMCPMC6858475
OpenAlexW2963321302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.