ArticleThe Journal of infectious diseases2019
Seroprevalence, Risk Factors, and Rodent Reservoirs of Leptospirosis in an Urban Community of Puerto Rico, 2015.
Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Estimating the burden of leptospirosis in the Caribbean: Insights from environmental and sociodemographic factors.PLoS neglected tropical diseases · 2026Article
- Leptospirosis in the Caribbean Region between 2000 and 2022: A scoping review of morbidity and mortality.PLoS neglected tropical diseases · 2026Article
- Article
- Policy Options for Prevention of Leptospirosis Epidemics: A Scoping Review.Iranian journal of public health · 2025Review
- Leptospirosis seroprevalence and exposure factors in three informal settlements of French Guiana: An opportunistic survey.PLoS neglected tropical diseases · 2025Article
- Quantifying Spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model.Scientific reports · 2025Article
- Diagnosis and Clinical Description of Leptospirosis Cases Identified Through Hospital-Based Active Surveillance in Puerto Rico, 2019-2021.Journal of tropical medicine · 2025Article
- Seroepidemiology of human leptospirosis in the Dominican Republic: A multistage cluster survey, 2021.PLoS neglected tropical diseases · 2024Article
- Leptospirosis Outbreak in Aftermath of Hurricane Fiona - Puerto Rico, 2022.MMWR. Morbidity and mortality weekly report · 2024Article
- Environmental and Occupational Factors Associated with Leptospirosis: A Systematic Review.Heliyon · 2024Article
- Seroprevalence of leptospirosis among blood donors in an endemic area.Scientific reports · 2023Article
- Animals Exposed toTropical medicine and infectious disease · 2023Article
- Article
- Leptospira Infection in Rural Areas of Urabá Region, Colombia: A Prospective Study.The American journal of tropical medicine and hygiene · 2022Article
- Article
- Diverse lineages of pathogenic Leptospira species are widespread in the environment in Puerto Rico, USA.PLoS neglected tropical diseases · 2022Article
- Assessing rodents as carriers of pathogenic Leptospira species in the U.S. Virgin Islands and their risk to animal and public health.Scientific reports · 2022Article
- Article
- Effect of Sewerage on the Contamination of Soil with PathogenicEnvironmental science & technology · 2021Article
- Article
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundThe burden of leptospirosis in Puerto Rico remains unclear due to underreporting.
methodsA cross-sectional survey and rodent trapping was performed in a community within San Juan, Puerto Rico to determine the seroprevalence and risk factors for Leptospira infection. The microscopic agglutination test was used to detect anti-Leptospira antibodies as a marker of previous infection. We evaluated Leptospira carriage by quantitative polymerase chain reaction among rodents trapped at the community site.
resultsOf 202 study participants, 55 (27.2%) had Leptospira agglutinating antibodies. Among the 55 seropositive individuals, antibodies were directed most frequently against serogroups Icterohaemorrhagiae (22.0%) and Autumnalis (10.6%). Of 18 captured rodents, 11 (61.1%) carried pathogenic Leptospira (Leptospira borgpetersenii, 7 and Leptospira interrogans, 2). Four participants showed their highest titer against an isolate obtained from a rodent (serogroup Ballum). Increasing household distance to the canal that runs through the community was associated with decreased risk of infection (odds ratio = 0.934 per 10-meter increase; 95% confidence interval, .952-.992).
conclusionsThere are high levels of Leptospira exposure in an urban setting in Puerto Rico, for which rodents may be an important reservoir for transmission. Our findings indicate that prevention should focus on mitigating risk posed by infrastructure deficiencies such as the canal.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.