Evidence map›Paper›PMID 31342057›Full record

Trial reportClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections.

Laura C Fanucchi, Sharon L Walsh, Alice C Thornton, Paul A Nuzzo, Michelle R Lofwall

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03048643 (CATS-CARE), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03048643 nacompletednot on this map

CATS-CARE: Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis

TypeinterventionalSponsorLaura FanucchiRan2017 to 2018Enrolled20ConditionsEndocarditis, Bacterial, Opioid-use Disorder, Buprenorphine, Outpatient Parenteral Antibiotic TherapyArmsOutpatient parenteral antibiotic therapy
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Infective Endocarditis in Pregnancy: A Contemporary Cohort.American journal of perinatology · 2024
    Article
  14. Article
  15. Review
  16. Frame Shift: Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Outcomes of Partial Oral Antibiotic Treatment for Complicated Staphylococcus aureus Bacteremia in People Who Inject Drugs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura C FanucchiDivision of Infectious Disease, Center on Drug and Alcohol Research, University of Kentucky, Lexington.
Sharon L WalshCenter on Drug and Alcohol Research, University of Kentucky, Lexington.
Alice C ThorntonDivision of Infectious Disease, University of Kentucky, Lexington.
Paul A NuzzoCenter on Drug and Alcohol Research, University of Kentucky, Lexington.
Michelle R LofwallCenter on Drug and Alcohol Research, University of Kentucky, Lexington.
University of Kentucky · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
NCATS NIH HHS UL1 TR001998
6 · The paper itself

Abstract

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. CLINICAL TRIALS REGISTRATION: NCT03048643.

Indexed as

Anti-Infective AgentsBuprenorphineOpioid-Related DisordersAnti-Bacterial AgentsHumansOpiate Substitution TreatmentOutpatientsAnti-Bacterial AgentsAnti-Infective AgentsBuprenorphineantibioticsbuprenorphineendocarditisinjection-drug useopioid-related disorders

Identifiers

PMID31342057
PMCPMC7931831
OpenAlexW2972224674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.