ArticleCommunications biology2019
Canine osteosarcoma genome sequencing identifies recurrent mutations in
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Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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78citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
What it found
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Who cites it
78 citing papers in PubMed, 124 citations in OpenAlex.
- Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers.Veterinary and comparative oncology · 2026Article
- Berberine Chloride Suppresses Growth of Canine Osteosarcoma Cells via Regulating MMP2/AKT/β-Catenin Pathway.Antioxidants (Basel, Switzerland) · 2026Article
- Integrated Multiomic Profiling Enhances Risk Stratification and Prognostication in Canine Osteosarcoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026Article
- Single-cell fixed RNA profiling of the osteosarcoma clinical Spectrum identifies ADAMTS12 and RNASE1 as key drivers of the metastatic niche.Journal of bone oncology · 2026Article
- Article
- Impact of preanalytical factors on liquid biopsy in the canine cancer model.Communications medicine · 2026Article
- Leveraging Dog Models to Uncover Human Cancer Insights.Research square · 2026Article
- The first limb-sparing use of histotripsy for canine osteosarcoma.Scientific reports · 2026Article
- Satellite DNA fragility accompanies complex genome rearrangements and ecDNA oncogene amplification in canine osteosarcomas.bioRxiv : the preprint server for biology · 2025Article
- Decoding osteosarcoma from heterogeneity to precision therapy.Discover oncology · 2025Review
- Expanding the Spectrum of Canine Diffuse Large B-Cell Lymphoma Genetic Aberrations Through Whole Genome Sequencing Analysis.Veterinary and comparative oncology · 2025Article
- Spatial Transcriptomics Advances the Use of Canine Patients in Cancer Research: Analysis of Osteosarcoma-Bearing Pet Dogs Enrolled in a Clinical Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Article
- Building a Therapeutic Bridge Between Dogs and Humans: A Review of Potential Cross-Species Osteosarcoma Biomarkers.International journal of molecular sciences · 2025Review
- Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology.Frontiers in molecular biosciences · 2025Review
- Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma.PloS one · 2025Article
- Comprehensive Analysis of Microsatellite Instability in Canine Cancers: Implications for Comparative Oncology and Personalized Veterinary Medicine.Animals : an open access journal from MDPI · 2024Article
- Anti-tumor effects of the eIF4A inhibitor didesmethylrocaglamide and its derivatives in human and canine osteosarcomas.Scientific reports · 2024Article
- The K9 lymphoma assay allows a genetic subgrouping of canine lymphomas with improved risk classification.Scientific reports · 2024Article
- Bringing the Genomic Revolution to Comparative Oncology: Human and Dog Cancers.Annual review of biomedical data science · 2024Review
- Impact of preanalytical factors on liquid biopsy in the canine cancer model.bioRxiv : the preprint server for biology · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 1 country.
Heather L Gardner1Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA 02111 USA.ORCID 0000-0001-6007-6144
Karthigayini Sivaprakasam2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Natalia Briones2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Victoria Zismann2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Nieves Perdigones2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Kevin Drenner2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Salvatore Facista2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Ryan Richholt2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Winnie Liang2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Jessica Aldrich2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Jeffrey M Trent2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.
Peter G Shields3College of Medicine, The Ohio State University, Columbus, OH 43210 USA.
Nicholas Robinson4Cummings School of Veterinary Medicine, Tufts University, Grafton, MA 01536 USA.
Jeremy Johnson5Broad Institute, Cambridge, MA 02142 USA.
Susan Lana6Colorado State University, Fort Collins, CO 80525 USA.
Peter Houghton7University of Texas Health Science Center, San Antonio, TX 78229 USA.
Joelle Fenger8Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH 43210 USA.
Gwendolen Lorch8Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH 43210 USA.ORCID 0000-0001-6443-704X
Katherine A Janeway9Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 USA.
Cheryl A London *4Cummings School of Veterinary Medicine, Tufts University, Grafton, MA 01536 USA.
William P D Hendricks *2Translational Genomics Research Institute, Phoenix, AZ 85004 USA.ORCID 0000-0001-7192-8699
Translational Genomics Research Institute · USThe Ohio State University · USTufts University · USBroad Institute · USColorado State University · USDana-Farber Cancer Institute · USThe University of Texas Health Science Center at San Antonio · US
Funding
VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI JENNIFER W MACK · 1985 to 2026
$330.6MTranslational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3MThe OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9MXENOGRAFT AND CELL LINE COREP01CA165995 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LONDON, CHERYL A · 2013 to 2017
$7.9MDissecting the role of miR-9 in normal and malignant mast cell biologyK01OD019923 · OD · OHIO STATE UNIVERSITY · PI FENGER, JOELLE M · 2015 to 2019
$654kNCATS NIH HHS UL1 TR002733NCI NIH HHS P01 CA165995NCI NIH HHS P30 CA006516NCI NIH HHS P30 CA016058NIH HHS K01 OD019923
Abstract
Osteosarcoma (OS) is a rare, metastatic, human adolescent cancer that also occurs in pet dogs. To define the genomic underpinnings of canine OS, we performed multi-platform analysis of OS tumors from 59 dogs, including whole genome sequencing (
Indexed as
MutationAnimalsBone NeoplasmsDogsDystrophinHistone-Lysine N-MethyltransferaseOsteosarcomaWhole Genome SequencingDystrophinHistone-Lysine N-MethyltransferaseBone cancerCancer genomicsDogSarcoma
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.