Evidence map›Paper›PMID 31341929›Full record

ArticleOpen forum infectious diseases2019

Trends in Diagnosed Chronic Hepatitis B in a US Health System Population, 2006-2015.

Mei Lu, Yueren Zhou, Scott D Holmberg, Anne C Moorman, Philip R Spradling, Eyasu H Teshale, Joseph A Boscarino, Yihe G Daida, Mark A Schmidt, Jia Li and 4 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Hepatitis B Care Continuum Models-Data to Inform Public Health Action.Public health reports (Washington, D.C. : 1974) · 2024
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mei LuDepartment of Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Yueren ZhouDepartment of Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Scott D HolmbergDivision of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta Georgia.
Anne C MoormanDivision of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta Georgia.
Philip R SpradlingDivision of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta Georgia.
Eyasu H TeshaleDivision of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta Georgia.
Joseph A BoscarinoDepartment of Epidemiology and Health Services Research, Geisinger Clinic, Danville, Pennsylvania.
Yihe G DaidaCenter for Health Research, Kaiser Permanente Hawaii, Honolulu, Hawai'i.
Mark A SchmidtCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
Jia LiDepartment of Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Loralee B RuppCenter for Health Policy and Health Services Research, Wayne State University School of Medicine, Detroit, Michigan.
Sheri TrudeauDepartment of Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Stuart C GordonDivision of Gastroenterology and Hepatology, Henry Ford Health System, and Wayne State University School of Medicine, Detroit, Michigan.
Chronic Hepatitis Cohort Study Investigators

Funding

ACL HHS U18PS005154
6 · The paper itself

Abstract

backgroundTrends in the epidemiology of chronic hepatitis B (CHB) among routine clinical care patients in the United States are not well documented. We used data from the Chronic Hepatitis Cohort Study to investigate changes in prevalence and newly recorded cases of CHB from 2006 to 2015.

methodsAnnual percentage changes (APCs) were estimated using join point Poisson regression. Analyses were adjusted by study site; when an interaction with the trend was observed, APCs were estimated by subgroups. Differences in rates based on race, age, and sex were calculated with rate ratios.

resultsWe identified 5492 patients with CHB within select health systems with total populations that ranged from 1.9 to 2.4 million persons. From 2006 to 2014, the prevalence of diagnosed CHB increased from 181.3 to 253.0 per 100 000 persons in the health system population; from 2014 to 2015, it declined to 237.0 per 100 000 persons. APC was +3.7%/y through 131 December 2014 (

conclusionsThe prevalence of diagnosed CHB in this US patient population increased from 2006 to 2014, after which it decreased significantly. Rates declined most rapidly among patients ≤40 or 61-70 years old, as well as among ASINPI patients. The rate of newly reported cases remained steady over the study period.

Indexed as

cirrhosis prevalencedecompensated cirrhosishepatocellular carcinoma (HCC)join point modelingliver transplant

Identifiers

PMID31341929
PMCPMC6641786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.