Evidence map›Paper›PMID 31341797›Full record

ArticleInternational journal of ophthalmology2019

Down regulation of UCP2 expression in retinal pigment epithelium cells under oxidative stress: an

Ying Liu, Yuan Ren, Xia Wang, Xu Liu, Yun Xu, Yuan He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying LiuDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Yuan RenDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Xia WangDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Xu LiuDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Yun XuDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Yuan HeDepartment of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University; Ocular Immunology and Inflammation Institute, Shaanxi Provincial Clinical Research Center for Ophthalmology, Xi'an 710038, Shaanxi Province, China.
Xi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the expression of uncoupling protein 2 (UCP2) in a retinal pigment epithelium cell line (ARPE-19), under oxidative stress (OS).

methodsARPE-19 cells were divided into groups treated with various concentrations of hydrogen peroxide (H

resultsCells treated with higher concentrations of H

conclusionExpression levels of UCP2 are decreased in ARPE-19 cells treated with H

Indexed as

oxidative stressretinal pigment epithelium cellsuncoupling protein 2

Identifiers

PMID31341797
PMCPMC6629815
OpenAlexW2961705167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.