Evidence map›Paper›PMID 31341707›Full record

ArticleNeurology. Clinical practice2019

Differences in treatment of epilepsy in pregnancy: A worldwide survey.

Ilena C George, Luca Bartolini, John Ney, Divya Singhal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Clinical practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilena C GeorgeCorinne Goldsmith Dickinson Center for Multiple Sclerosis (ICG), Mount Sinai, New York, NY; Clinical Epilepsy Section (LB), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Center for Neuroscience (LB), George Washington University, Children's National Health System; Center for Healthcare Organization and Implementation Research (JN), Edith Nourse Rogers Memorial VA, Bedford, MA; and Department of Neurology (DS), University of Oklahoma.
Luca BartoliniCorinne Goldsmith Dickinson Center for Multiple Sclerosis (ICG), Mount Sinai, New York, NY; Clinical Epilepsy Section (LB), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Center for Neuroscience (LB), George Washington University, Children's National Health System; Center for Healthcare Organization and Implementation Research (JN), Edith Nourse Rogers Memorial VA, Bedford, MA; and Department of Neurology (DS), University of Oklahoma.
John NeyCorinne Goldsmith Dickinson Center for Multiple Sclerosis (ICG), Mount Sinai, New York, NY; Clinical Epilepsy Section (LB), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Center for Neuroscience (LB), George Washington University, Children's National Health System; Center for Healthcare Organization and Implementation Research (JN), Edith Nourse Rogers Memorial VA, Bedford, MA; and Department of Neurology (DS), University of Oklahoma.
Divya SinghalCorinne Goldsmith Dickinson Center for Multiple Sclerosis (ICG), Mount Sinai, New York, NY; Clinical Epilepsy Section (LB), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Center for Neuroscience (LB), George Washington University, Children's National Health System; Center for Healthcare Organization and Implementation Research (JN), Edith Nourse Rogers Memorial VA, Bedford, MA; and Department of Neurology (DS), University of Oklahoma.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHow to safely treat pregnant women with epilepsy is a question for which there are guidelines, but variations in practice exist.

methodsTo better characterize how clinicians address this difficult clinical question, we distributed an anonymous survey to neurology practitioners across subspecialties and different levels of training via the

resultsThe results of this survey demonstrate a wide range in the amount of folic acid recommended and the frequency of checking levels of anti-epileptic drugs. Choice of first-line agent varied by the economic development status of the respondent's country, suggesting that access to medications plays an important role in clinical decision making in many parts of the world.

conclusionThis survey highlights several areas where further research would be helpful in guiding practice.

Identifiers

PMID31341707
PMCPMC6615647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.