ArticleEvoDevo2019
Conservation and flexibility in the gene regulatory landscape of heliconiine butterfly wings.
Article in EvoDevo, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies.Biology open · 2025Article
- From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology.Molecular ecology · 2025Review
- Article
- Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies.PLoS biology · 2025Article
- A long noncoding RNA at theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Frizzled2 receives WntA signaling during butterfly wing pattern formation.Development (Cambridge, England) · 2023Article
- Antibody development to identify components of IIS and mTOR signaling pathways in lepidopteran species, a set of non-model insects.microPublication biology · 2023Article
- A large deletion at the cortex locus eliminates butterfly wing patterning.G3 (Bethesda, Md.) · 2022Article
- Review
- Stage- and sex-specific transcriptome analyses reveal distinctive sensory gene expression patterns in a butterfly.BMC genomics · 2021Article
- Heliconius butterflies: a window into the evolution and development of diversity.Current opinion in genetics & development · 2021Review
- A widely diverged locus involved in locomotor adaptation inScience advances · 2021Article
- Article
- Genomics Reveals the Origins of Historical Specimens.Molecular biology and evolution · 2021Article
- Perfect mimicry betweenProceedings. Biological sciences · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundMany traits evolve by
resultsWe investigated the spatial transcriptomic landscape across the wings of three closely related butterfly species, two of which have a convergently evolved co-mimetic pattern and the other having a divergent pattern. We identified candidate factors for regulating the expression of wing patterning genes, including transcription factors with a conserved expression profile in all three species, and others, including both transcription factors and Wnt pathway genes, with markedly different profiles in each of the three species. We verified the conserved expression profile of the transcription factor homothorax by immunofluorescence and showed that its expression profile strongly correlates with that of the selector gene optix in butterflies with the Amazonian forewing pattern element 'dennis.'
conclusionHere we show that, in addition to factors with conserved expression profiles like homothorax, there are also a variety of transcription factors and signaling pathway components that appear to vary in their expression profiles between closely related butterfly species, highlighting the importance of genome-wide regulatory evolution between species.
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