Evidence map›Paper›PMID 31341569›Full record

ArticleIranian journal of microbiology2019

Effect of the probiotic

Reza Ranuh, Alpha Fardah Athiyyah, Andy Darma, Vitria Prasetyo Risky, Wibi Riawan, Ingrid S Surono, Subijanto Marto Sudarmo

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05945017 (Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05945017 naactive not recruitingnot on this map

Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g

TypeinterventionalSponsorFundacion Clinic per a la Recerca BiomédicaRan2014 to 2027Enrolled233ConditionsInfant, Newborn, Diseases, Infant DevelopmentArmsInfloran® -Berne, Switzerland- (Bifidobacterium bifidum NCDO 2203 and Lactobacillus acidophilus NCDO 1748
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Efficacy and dose response ofWorld journal of gastroenterology · 2023
    Trial
  6. Trial
  7. Nutrients · 2020
    Trial
  8. Trial
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Preventive Effect of ProbioticAntioxidants (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Microbiota influence on behavior: Integrative analysis of serotonin metabolism and behavioral profile in germ-free mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Reza RanuhDepartment of Child Health, Dr. Soetomo Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.
Alpha Fardah AthiyyahDepartment of Child Health, Dr. Soetomo Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.
Andy DarmaDepartment of Child Health, Dr. Soetomo Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.
Vitria Prasetyo RiskyDepartment of Child Health, Dr. Soetomo Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.
Wibi RiawanDepartment of Biomolecular Laboratory, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Ingrid S SuronoDepartment of Food Technology, Faculty of Engineering, Bina Nusantara University, Jakarta, Indonesia.
Subijanto Marto SudarmoDepartment of Child Health, Dr. Soetomo Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.
Airlangga University · IDBinus University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesMicrobial communities residing in the gut play a major role in the communication between the gut and the brain through neural, immune, and hormonal routes. Changes in abundance of beneficial intestinal bacteria can affect health of individuals. Conversely, drugs, disease, diet and other factors can alter the gut microbiome. However, there is limited information on the effect of exogenous factors on gut microbiota. In this study, we investigated whether a beneficial bacterium, the probiotic MATERIALS AND

methodsThe animals were divided into two groups: one received

resultsThe results showed that BDNF (

conclusionThe probiotic

Indexed as

Brain-derived neurotrophic factorGut–brain axisProbiotic Lactobacillus plantarum IS 10506Serotonin

Identifiers

PMID31341569
PMCPMC6635314
OpenAlexW2947027948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.