ArticleIranian journal of microbiology2019
Identification of microorganisms in persistent/secondary endodontic infections with respect to clinical and radiographic findings: bacterial culture and molecular detection.
Article in Iranian journal of microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Biological response to endodontic treatment in one versus two-visit: a systematic review and meta-analysis of animal studies.Clinical oral investigations · 2024Pooled it
- Pooled it
- Effect of different rotary instrument designs (protaper ultimate and protaper gold) on postoperative pain and bacterial reduction: a randomized clinical trial.BMC oral health · 2026Trial
- CLSM-guided imaging provides new insights into position-dependent limitations of endodontic disinfection.Clinical oral investigations · 2026Article
- Is apical periodontitis a matter of microbial diversity or time? A scoping review.Head & face medicine · 2026Article
- Bioactive peptides in Endodontic infections: The Good, The Bad, and The Ugly.Probiotics and antimicrobial proteins · 2026Review
- Identification and quantification ofFrontiers in dental medicine · 2026Article
- Antibacterial Effect of Cannabinoids on Bacteria Associated with Persistent Endodontic Infections.International journal of molecular sciences · 2025Article
- CLSM-Guided Imaging to Visualize the Depth of Effective Disinfection in Endodontics.Antibiotics (Basel, Switzerland) · 2025Article
- Efficacy of antimicrobial photodynamic therapy for bacterial reduction in endodontics of primary teeth: an in vitro study.Lasers in medical science · 2025Article
- Association between root canals and gingival sulci microbiota in secondary and persistent endodontic infections.Scientific reports · 2025Article
- A Comparison of Conventional Root Canal Sealers With Ones That Use Green Synthesized Nanoparticles for Antimicrobial Activity: Protocol for a Systematic Review.JMIR research protocols · 2024Article
- CLSM-Guided Imaging for Quantifying Endodontic Disinfection.Antibiotics (Basel, Switzerland) · 2024Article
- Review
- Bacteria associated with apical periodontitis promotes in vitro the differentiation of macrophages to osteoclasts.Clinical oral investigations · 2023Article
- Inflammation at Site of Insulin Infusion Diminishes Glycemic Control.Journal of pharmaceutical sciences · 2022Article
- Antibacterial Effect of Endodontic Disinfections on Enterococcus Faecalis in Dental Root Canals-An In-Vitro Model Study.Materials (Basel, Switzerland) · 2021Article
- Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells.International journal of molecular sciences · 2020Article
- Quantification of Bacterial Colonization in Dental Hard Tissues Using Optimized Molecular Biological Methods.Frontiers in genetics · 2020Article
- Antibacterial efficacy of antibiotic pastes versus calcium hydroxide intracanal dressing: A systematic review and meta-analysis ofJournal of conservative dentistry : JCDReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesBacterial agents are commonly accepted as the main etiology of endodontic infections. A significant proportion of oral bacteria cannot be cultured using existing methods. Since diversity and abundance of bacterial species are different in different populations, the present study was aimed to identify effective microorganisms in persistent endodontic infections in Iranian patients based on culture and molecular biology methods using sequence analysis of 16S rDNA gene. MATERIALS AND
methodsThirty patients with previous failure of endodontic treatment were enrolled in the study. After isolation and disinfection of the tooth surrounding area with 3% sodium hypochlorite and 30% hydrogen peroxide, sampling from the root canals was carried out using two sterile Hedstrom files and two sterile paper points, and then the specimens were transferred to the microbiology laboratory in thioglycolate transport medium so that they undergo aerobic-anaerobic culture, PCR, and 16S rDNA gene sequencing.
resultsOf 30 patients (15 women and 15 men), 15 patients had radiographic lesions smaller than 5 mm and other 15 patients had radiographic lesions larger than 5 mm. The mean age of patients was 40.20 ± 13.76 years. A total of 26 patients were asymptomatic. Only four patients had clinical signs such as pain and percussion sensitivity and
conclusionThis study showed the type and prevalence of effective bacteria in secondary/persistent endodontic infections in Iranian patients.
Indexed as
Identifiers
31341566PMC6635307W2947157643What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.