ArticleThe open epidemiology journal2011
Leveraging Epidemiology to Improve Risk Assessment.
Article in The open epidemiology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- iPSC-Derived Bronchial Airways-On-Chip for the Assessment of Cytokine Secretion Triggered by Volatile Organic Compounds.ACS biomaterials science & engineering · 2026Article
- Expert perspectives on exposure-response functions for urban health policy: Lessons from a UBDPolicy workshop.Environmental research · 2026Review
- A Perspective from US Environmental Protection Agency (EPA) Scientists: How Your Epidemiologic Analyses Can Inform the Human Health Risk Assessment Process.Environmental health perspectives · 2025Article
- Practical Opportunities to Improve the Impact of Health Risk Assessment on Environmental and Public Health Decisions.International journal of environmental research and public health · 2022Article
- Charting a Path Forward: Assessing the Science of Chemical Risk Evaluations under the Toxic Substances Control Act in the Context of Recent National Academies Recommendations.Environmental health perspectives · 2022Article
- Probabilistic health risk assessment of chlorpyrifos exposure among applicators on rice farms in Ghana.Environmental science and pollution research international · 2021Article
- Environmental Health Risk Assessment in the Federal Government: A Visual Overview and a Renewed Call for Coordination.Environmental science & technology · 2021Article
- A two-step gas chromatography-tandem mass spectrometry method for measurement of multiple environmental pollutants in human plasma.Environmental science and pollution research international · 2021Article
- Epidemiology: a foundation of environmental decision making.Journal of exposure science & environmental epidemiology · 2018Review
- Scientific Opinion of the PPR Panel on the follow-up of the findings of the External Scientific Report 'Literature review of epidemiological studies linking exposure to pesticides and health effects'.EFSA journal. European Food Safety Authority · 2017Article
- Towards a systemic paradigm in carcinogenesis: linking epigenetics and genetics.Molecular biology reports · 2015Article
- Environmental determinants of chronic disease and medical approaches: recognition, avoidance, supportive therapy, and detoxification.Journal of environmental and public health · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The field of environmental public health is at an important crossroad. Our current biomonitoring efforts document widespread exposure to a host of chemicals for which toxicity information is lacking. At the same time, advances in the fields of genomics, proteomics, metabolomics, genetics and epigenetics are yielding volumes of data at a rapid pace. Our ability to detect chemicals in biological and environmental media has far outpaced our ability to interpret their health relevance, and as a result, the environmental risk paradigm, in its current state, is antiquated and ill-equipped to make the best use of these new data. In light of new scientific developments and the pressing need to characterize the public health burdens of chemicals, it is imperative to reinvigorate the use of environmental epidemiology in chemical risk assessment. Two case studies of chemical assessments from the Environmental Protection Agency Integrated Risk Information System database are presented to illustrate opportunities where epidemiologic data could have been used in place of experimental animal data in dose-response assessment, or where different approaches, techniques, or studies could have been employed to better utilize existing epidemiologic evidence. Based on the case studies and what can be learned from recent scientific advances and improved approaches to utilizing human data for dose-response estimation, recommendations are provided for the disciplines of epidemiology and risk assessment for enhancing the role of epidemiologic data in hazard identification and dose-response assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.