ArticleScientific reports2019
Heart Rhythm Complexity Impairment in Patients with Pulmonary Hypertension.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04554160 (ArrhythmiaS in Pulmonary arterIal hypeRtEnsion and Right Heart Failure Assessed by Continuous Long-term Cardiac Monitoring), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ArrhythmiaS in Pulmonary arterIal hypeRtEnsion and Right Heart Failure Assessed by Continuous Long-term Cardiac Monitoring
Who cites it
14 citing papers in PubMed.
- Temporal Changes in Nonlinear Heart Rate Variability Following Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation.Acta Cardiologica Sinica · 2026Article
- Preselected and preferred immersive virtual reality versus narrative alone to induce post-stress relaxation in patients with pulmonary arterial hypertension: A pilot study on perceived stress and heart rate.British journal of health psychology · 2026Article
- 'Hidden' anger as a risk factor for operational health: An exploratory approach among French military personnel.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025Article
- Early detection of subclinical heart disease via nonlinear heart rate variability in a doxorubicin-induced cardiomyopathy experimental model in dogs.Frontiers in veterinary science · 2025Article
- Analysis of changes in heart rate variability after prolonged ultra-high plateau residence in young healthy population: a cross-sectional study.Frontiers in physiology · 2025Article
- Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction.Scientific reports · 2023Article
- Real-time machine learning model to predict in-hospital cardiac arrest using heart rate variability in ICU.NPJ digital medicine · 2023Article
- Skin sympathetic nerve activity as a biomarker for outcomes in spontaneous intracerebral hemorrhage.Annals of clinical and translational neurology · 2023Article
- Continuous long-term heart rate variability and risk assessment in pulmonary hypertension.Open heart · 2023Article
- Physiological and Psychological Response to Acute Mental Stress in Female Patients Affected by Chronic Pulmonary Arterial Hypertension: An Explorative Controlled Pilot Trial.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Article
- The Value of Heart Rhythm Complexity in Identifying High-Risk Pulmonary Hypertension Patients.Entropy (Basel, Switzerland) · 2021Article
- CEPS: An Open Access MATLAB Graphical User Interface (GUI) for the Analysis of Complexity and Entropy in Physiological Signals.Entropy (Basel, Switzerland) · 2021Article
- Usefulness of heart rhythm complexity in heart failure detection and diagnosis.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary hypertension is a fatal disease, however reliable prognostic tools are lacking. Heart rhythm complexity analysis is derived from non-linear heart rate variability (HRV) analysis and has shown excellent performance in predicting clinical outcomes in several cardiovascular diseases. However, heart rhythm complexity has not previously been studied in pulmonary hypertension patients. We prospectively analyzed 57 patients with pulmonary hypertension (31 with pulmonary arterial hypertension and 26 with chronic thromboembolic pulmonary hypertension) and compared them to 57 age- and sex-matched control subjects. Heart rhythm complexity including detrended fluctuation analysis (DFA) and multiscale entropy (MSE) and linear HRV parameters were analyzed. The patients with pulmonary hypertension had significantly lower mean RR, SDRR, pNN
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