Evidence map›Paper›PMID 31341168›Full record

ArticleScientific data2019

Temporally replicated DNA methylation patterns in great tit using reduced representation bisulfite sequencing.

Hannu Mäkinen, Heidi M Viitaniemi, Marcel E Visser, Irene Verhagen, Kees van Oers, Arild Husby

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Hannu MäkinenOrganismal and Evolutionary Biology Research Programme, University of Helsinki, Helsinki, Finland. hannu.makinen@ebc.uu.se.
Heidi M ViitaniemiOrganismal and Evolutionary Biology Research Programme, University of Helsinki, Helsinki, Finland.
Marcel E VisserDepartment of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands.ORCID http://orcid.org/0000-0002-1456-1939
Irene VerhagenDepartment of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands.
Kees van OersDepartment of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands.
Arild HusbyOrganismal and Evolutionary Biology Research Programme, University of Helsinki, Helsinki, Finland. arild.husby@ebc.uu.se.
Netherlands Institute of Ecology · NLUppsala University · SEUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seasonal timing of reproduction is an important fitness trait in many plants and animals but the underlying molecular mechanism for this trait is poorly known. DNA methylation is known to affect timing of reproduction in various organisms and is therefore a potential mechanism also in birds. Here we describe genome wide data aiming to detect temporal changes in methylation in relation to timing of breeding using artificial selection lines of great tits (Parus major) exposed to contrasting temperature treatments. Methylation levels of DNA extracted from erythrocytes were examined using reduced representation bisulfite sequencing (RRBS). In total, we obtained sequencing data from 63 libraries over four different time points from 16 birds with on average 20 million quality filtered reads per library. These data describe individual level temporal variation in DNA methylation throughout the breeding season under experimental temperature regimes and provides a resource for future studies investigating the role of temporal changes in DNA methylation in timing of reproduction.

Indexed as

DNA MethylationTemperatureAnimalsBreedingFemalePasseriformesReproductionSeasonsSequence Analysis, DNA

Identifiers

PMID31341168
PMCPMC6656709
OpenAlexW2963854188

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.