Evidence map›Paper›PMID 31341075›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.

Xin Zhang, Nazanin Kiapour, Sahil Kapoor, Tabish Khan, Madhan Thamilarasan, Yazhong Tao, Stephanie Cohen, Ryan Miller, Raymond A Sobel, Silva Markovic-Plese

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 64 citations in OpenAlex.

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  10. The Role of Killer Ig-like Receptors in Diseases from A to Z.International journal of molecular sciences · 2025
    Review
  11. Genes · 2025
    Review
  12. Article
  13. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xin ZhangDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Nazanin KiapourDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-7473-415X
Sahil KapoorDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0003-3553-382X
Tabish KhanDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Madhan ThamilarasanDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Yazhong TaoDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Stephanie CohenLineberger Cancer Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Ryan MillerDepartment of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-0096-8762
Raymond A SobelDepartment of Pathology, Stanford University, Palo Alto, CA 94394.ORCID 0000-0002-0477-9002
Silva Markovic-PleseDepartment of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; silva.markovic-plese@jefferson.edu.
University of North Carolina at Chapel Hill · USPalo Alto University · US

Funding

The Role of IL-II in the development of autoimmune response in multiple sclerosisR01AI131238 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI MARKOVIC-PLESE, SILVA · 2018 to 2022
$2.0M
The Role of IL-11 in Development of Th17-mediated Autoimmune Response in EAER03AI111592 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARKOVIC-PLESE, SILVA · 2014 to 2015
$152k
NIAID NIH HHS R01 AI131238NIAID NIH HHS R03 AI111592
6 · The paper itself

Abstract

IL-11

Indexed as

AdultAgedAnimalsCD4-Positive T-LymphocytesEncephalomyelitis, Autoimmune, ExperimentalFemaleHumansInterleukin-11Interleukin-17MiceMiddle AgedMultiple Sclerosis, Relapsing-RemittingReceptors, CCR6Spinal CordTh17 CellsInterleukin-11Interleukin-17Receptors, CCR6

Identifiers

PMID31341075
PMCPMC6697738
OpenAlexW2963922095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.