Evidence map›Paper›PMID 31340691›Full record

ArticleJournal of dental research2019

W Chen, A Alshaikh, S Kim, J Kim, C Chun, S Mehrazarin, J Lee, R Lux, R H Kim, K H Shin and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Anaerobe-Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Vitamin DInternational journal of molecular sciences · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. hTERT Peptide Fragment GV1001 Prevents the Development ofInternational journal of molecular sciences · 2024
    Article
  20. Role of ferroptosis inJournal of oral microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

W Chen1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
A Alshaikh1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
S Kim1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
J Kim1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
C Chun1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
S Mehrazarin1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
J Lee1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
R Lux3 Section of Periodontics, Division of Constitutive and Regenerative Sciences, UCLA School of Dentistry, Los Angeles, CA, USA.
R H Kim1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
K H Shin1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
N H Park1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
K Walentin5 Max Delbruck Center for Molecular Medicine and Department of Nephrology, Charité Medical University, Berlin, Germany.
K M Schmidt-Ott5 Max Delbruck Center for Molecular Medicine and Department of Nephrology, Charité Medical University, Berlin, Germany.ORCID 0000-0002-7700-7142
M K Kang1 The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA, USA.
University of California, Los Angeles · USMax Delbrück Center · DE

Funding

Role of histone demethylase Kdm3C in age-associated oral and systemic inflammationR21DE028269 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG, KANG, MO K. · 2018 to 2019
$429k
Epigenetic role of GRHL2 in HPV-associated oral cancerR56DE024593 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KANG, MO K. · 2014 to 2014
$284k
Epigenetic regulation of radiation damage in oral mucosaR03DE024259 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, WEI · 2015 to 2016
$231k
NIDCR NIH HHS R03 DE024259NIDCR NIH HHS R21 DE028269NIDCR NIH HHS R56 DE024593
6 · The paper itself

Abstract

Oral mucosa provides the first line of defense against a diverse array of environmental and microbial irritants by forming the barrier of epithelial cells interconnected by multiprotein tight junctions (TJ), adherens junctions, desmosomes, and gap junction complexes. Grainyhead-like 2 (GRHL2), an epithelial-specific transcription factor, may play a role in the formation of the mucosal epithelial barrier, as it regulates the expression of the junction proteins. The current study investigated the role of GRHL2 in the

Indexed as

Tight JunctionsAnimalsCells, CulturedDNA-Binding ProteinsEpithelial CellsHumansIn Situ Hybridization, FluorescenceMiceMice, KnockoutMouth MucosaPorphyromonas gingivalisTranscription FactorsDNA-Binding Proteinsgrainy head-like 2 protein, mouseGRHL2 protein, humanTranscription Factorscell adhesiongene knockout techniqueslipopolysaccharidesoral mucosaperiodontal diseasestight junctions

Identifiers

PMID31340691
PMCPMC6704429
OpenAlexW2963304687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.