Evidence map›Paper›PMID 31340471›Full record

ArticleInternational journal of molecular sciences2019

Acute Cytotoxic Effects on Morphology and Mechanical Behavior in MCF-7 Induced by TiO

Mariafrancesca Cascione, Valeria De Matteis, Giacomo Mandriota, Stefano Leporatti, Rosaria Rinaldi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Design-ExpertPharmaceutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mariafrancesca CascioneDepartment of Mathematics and Physics "E. De Giorgi", University of Salento, Via Monteroni, 73100 Lecce, Italy. mariafrancesca.cascione@unisalento.it.
Valeria De MatteisDepartment of Mathematics and Physics "E. De Giorgi", University of Salento, Via Monteroni, 73100 Lecce, Italy.
Giacomo MandriotaIIT-Italian Institute of Technology, via Morego 30, 16163 Genova, Italy.
Stefano LeporattiCNR Nanotec-Institute of Nanotechnology, 73100 Lecce, Italy. stefano.leporatti@nanotec.cnr.it.ORCID 0000-0001-5912-7565
Rosaria RinaldiDepartment of Mathematics and Physics "E. De Giorgi", University of Salento, Via Monteroni, 73100 Lecce, Italy.
University of Salento · ITIstituto Nanoscienze · ITItalian Institute of Technology · IT

Funding

"POR Puglia FESR-FSE 2014-2020 - Asse prioritario 1 - Ricerca, sviluppo tecnologico, innovazione - Azione 1.6 "Interventi per il rafforzamento del sistema innovativo regionale e nazionale e incremento della collaborazione tra imprese e strutture di ricerc - BANDO INNONETWORK - Aiuti a sostegno alle Attività di R&S"."Progetto FISR-CNR - Tecnopolo di Nanotecnologia e Fotonica per la Medicina di precisione" CUP B83B17000010001.
6 · The paper itself

Abstract

The side effects induced by nanoparticle exposure at a cellular level are one of the priority research topics due to the steady increase in the use of nanoparticles (NPs). Recently, the focus on cellular morphology and mechanical behavior is gaining relevance in order to fully understand the cytotoxic mechanisms. In this regard, we have evaluated the morphomechanical alteration in human breast adenocarcinoma cell line (MCF-7) exposed to TiO

Indexed as

Actin CytoskeletonBiomechanical PhenomenaCell MembraneCell NucleusCell SurvivalCytosolCytotoxinsElasticityHumansMCF-7 CellsMicroscopy, Atomic ForceNanoparticlesTitaniumCytotoxinsTitaniumtitanium dioxidebiomechanicscytotoxicityscanning force microscopy

Identifiers

PMID31340471
PMCPMC6678441
OpenAlexW2962796853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.