SynthesisInternational journal of molecular sciences2019
Effect of Photodynamic Therapy on Microorganisms Responsible for Dental Caries: A Systematic Review and Meta-Analysis.
Synthesis in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 87 citations in OpenAlex.
- Microbial Composition of Carious Dentin and the Impact of Minimally Invasive Excavation Techniques: A Narrative Review.International journal of molecular sciences · 2026Review
- Antimicrobial Efficacy of Photodynamic Therapy as an Adjunct to Brix 3000 in Minimally Invasive Management of Carious Lesions in Primary Teeth.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Activity of antimicrobial photodynamic therapy against a cariogenic biofilm composed of a microbial consortium.Journal of biomedical optics · 2025Article
- Development of a Methylene Blue Carrier System in Gellan Gum for Application in Antimicrobial Photodynamic Therapy againstACS omega · 2025Article
- Effectiveness of biofilm-targeted therapy in managing and preventing dental caries: protocol for a systematic review and meta-analysis.Systematic reviews · 2025Article
- Antimicrobial photodynamic therapy and deproteinization in teeth with molar incisor hypomineralization: a case series.Translational pediatrics · 2025Article
- Curcumin-photosensitized nanocapsules: biocompatibility and antimicrobial evaluation in primary tooth dentin contaminated withFrontiers in cellular and infection microbiology · 2025Article
- Potentiation of antimicrobial photodynamic therapy with potassium iodide and methylene blue: targeting oral biofilm viability.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Beyond Antibiotics: What the Future Holds.Antibiotics (Basel, Switzerland) · 2024Review
- Article
- Efficiency of the photodynamic therapy on viability of Streptococcus mutans in the oral cavity using chitosan nanoparticles: an in vitro study.Lasers in medical science · 2024Article
- Color Changes in Artificially Induced Incipient Caries after Photodynamic Therapy with Different Concentrations of Methylene Blue and Toluidine Blue and Irrigation with Water and Hypochlorite.International journal of dentistry · 2024Article
- Article
- Potential Use of Brazilian Green Propolis Extracts as New Photosensitizers for Antimicrobial Photodynamic Therapy against Cariogenic Microorganisms.Pathogens (Basel, Switzerland) · 2023Article
- In Vitro Evaluation of Photodynamic Activity of Plant Extracts fromPharmaceutics · 2023Article
- Biofilm Lifestyle in Recurrent Urinary Tract Infections.Life (Basel, Switzerland) · 2023Review
- Efficacy of antiseptics and chemomechanical methods for dentin caries lesions: A systematic review with GRADE approach.Frontiers in oral health · 2023Review
- Efficacy of Antimicrobial Photodynamic Therapy Mediated by Photosensitizers Conjugated with Inorganic Nanoparticles: Systematic Review and Meta-Analysis.Pharmaceutics · 2022Review
- The Effect of Photodynamic Therapy on Oral-Premalignant Lesions: A Systematic Review.Journal of clinical and experimental dentistry · 2022Review
- Antibacterial Effect of Red Laser Therapy onInternational journal of dentistry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The aim of this study was to perform a systematic review of the literature followed by a meta-analysis about the efficacy of photodynamic therapy (PDT) on the microorganisms responsible for dental caries. The research question and the keywords were constructed according to the PICO strategy. The article search was done in Embase, Lilacs, Scielo, Medline, Scopus, Cochrane Library, Web of Science, Science Direct, and Pubmed databases. Randomized clinical trials and in vitro studies were selected in the review. The study was conducted according the PRISMA guideline for systematic review. A total of 34 articles were included in the qualitative analysis and four articles were divided into two subgroups to perform the meta-analysis. Few studies have achieved an effective microbial reduction in microorganisms associated with the pathogenesis of dental caries. The results highlight that there is no consensus about the study protocols for PDT against cariogenic microorganisms, although the results showed the PDT could be a good alternative for the treatment of dental caries.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.