ArticleSao Paulo medical journal = Revista paulista de medicina2019
Preoperative vitamin D deficiency is a risk factor for postoperative hypocalcemia in patients undergoing total thyroidectomy: retrospective cohort study.
Article in Sao Paulo medical journal = Revista paulista de medicina, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Risk factors for postoperative hypocalcaemia after thyroidectomy: A systematic review and meta-analysis.The Journal of international medical research · 2021Pooled it
- Development and validation of an explainable web-based machine learning model for predicting early postoperative hypocalcemia in patients with differentiated thyroid cancer.Gland surgery · 2026Article
- Prevalence and Predictors of Postoperative Hypoparathyroidism: A Multicenter Observational Study.Journal of clinical medicine · 2025Article
- The effect of preoperative vitamin D values on hypocalcemia after total thyroidectomy.Turkish journal of surgery · 2024Article
- A prospective cross-sectional study on hypocalcemia after total thyroidectomy in patients with Graves' disease: insights on secondary hyperparathyroidism.Surgery today · 2024Article
- Article
- Predictors of Postoperative Hypocalcemia and Hypoparathyroidism Following Thyroidectomy in Hanoi, Vietnam.International journal of endocrinology and metabolism · 2024Article
- Significant role of 1,25-dihydroxyvitamin D on serum calcium levels after total thyroidectomy: a prospective cohort study.Frontiers in endocrinology · 2024Article
- Preoperative Vitamin.D Status and Post-Total Thyroidectomy Hypocalcemia.Iranian journal of otorhinolaryngology · 2024Article
- Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer.Annals of pediatric endocrinology & metabolism · 2023Article
- Factors influencing serum calcium levels and the incidence of hypocalcemia after parathyroidectomy in primary hyperparathyroidism patients.Frontiers in endocrinology · 2023Article
- Preoperative vitamin D level is significantly associated with hypocalcemia after total thyroidectomy.BMC musculoskeletal disorders · 2022Article
- Vitamin D Deficiency Reduces Postthyroidectomy Protracted Hypoparathyroidism Risk. Is Gland Preconditioning Possible?Journal of the Endocrine Society · 2022Article
- Adverse events in thyroid surgery: observational study in three surgical units with high volume/year.BMC surgery · 2021Observational
- [Review of clinical practice guidelines for hypoparathyroidism].Problemy endokrinologii · 2021Review
- Preoperative vitamin D deficiency is associated with increased risk of postoperative hypocalcemia after total thyroidectomy.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- A Prospective Study of Vitamin D Supplement in Thyroidectomy Patients Based on Relative Decline of Parathyroid Hormone.Frontiers in pharmacology · 2021Article
- Vitamin D Insufficiency Predicts Susceptibility of Parathyroid Hormone Reduction after Total Thyroidectomy in Thyroid Cancer Patients.International journal of endocrinology · 2021Article
- Risk Factors for Severe Hypocalcemia in Patients with Secondary Hyperparathyroidism after Total Parathyroidectomy.International journal of endocrinology · 2021Article
- Hypocalcemia After Completion Thyroidectomy for Papillary Thyroid Carcinoma.Acta clinica Croatica · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between preoperative vitamin D deficiency and postoperative hypocalcemia in cases of total thyroidectomy (TT) is a matter of controversy and may vary according to geographical scenarios and populations.
objectiveThe objective here was to evaluate whether preoperative vitamin D deficiency was associated with postoperative symptomatic hypocalcemia in a population in South America. DESIGN AND
settingRetrospective cohort study on data from all patients undergoing total thyroidectomy, with or without central compartment lymph node dissection, from January 2014 to December 2017, at the A. C. Camargo Cancer Center.
methodsPatients with benign thyroid disease (Graves' disease, multinodular goiter or hyperthyroidism) or thyroid cancer who underwent primary total thyroidectomy with or without central compartment lymph node dissection were included. The exclusion criteria were simultaneous parathyroidectomy and conditions that could affect serum calcium levels. The data collected included patient demographics, thyroid pathology, extent of the surgical procedure and complications. Information on preoperative and postoperative calcium, parathyroid hormone (PTH) and vitamin D levels were retrieved from the medical records.
results1,347 patients were assessed and postoperative hypocalcemia was diagnosed in 284 patients (21%). The vitamin D levels were considered deficient in 243 patients (18%). Postoperative hypocalcemia was diagnosed in 357 patients (31.5%). Multivariate analysis showed that central compartment dissection and preoperative total calcium and deficient vitamin D levels were significant risk factors for postoperative hypocalcemia.
conclusionDeficient preoperative vitamin D levels were a significant risk factor for postoperative hypocalcemia. Preoperative oral supplementation should be considered, to minimize this risk.
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