Evidence map›Paper›PMID 31339774›Full record

ArticleAmerican journal of physiology. Renal physiology2019

In vivo measurements of kidney glomerular number and size in healthy and Os

Edwin J Baldelomar, Jennifer R Charlton, Kimberly A deRonde, Kevin M Bennett

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Are noninvasive measurements of nephron number achievable in humans?Current opinion in nephrology and hypertension · 2026
    Review
  2. Article
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  6. Development and Use of Human RecombinantACS applied bio materials · 2024
    Article
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  12. Article
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  15. Small Blob Detector Using Bi-Threshold Constrained Adaptive Scales.IEEE transactions on bio-medical engineering · 2021
    Article
  16. Review
  17. New imaging tools to measure nephron numberJournal of developmental origins of health and disease · 2021
    Review
  18. Nephron number and its determinants: a 2020 update.Pediatric nephrology (Berlin, Germany) · 2021
    Article
  19. Mapping nephron mass in vivo using positron emission tomography.American journal of physiology. Renal physiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Edwin J BaldelomarMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Jennifer R CharltonUniversity of Virginia Children's Hospital, Department of Pediatrics, Charlottesville, Virginia.
Kimberly A deRondeUniversity of Virginia Children's Hospital, Department of Pediatrics, Charlottesville, Virginia.
Kevin M BennettMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
University of Virginia Children's Hospital · USMallinckrodt (United States) · USWashington University in St. Louis · US

Funding

94 TESLA MR SCANNER FOR MURINE IMAGING: IMAGINGS10RR019911 · NCRR · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI BERR, STUART S · 2005 to 2005
$2.0M
Comprehensive MRI-based evaluation of human renal microstructureR01DK111861 · NIDDK · UNIVERSITY OF VIRGINIA · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2020
$1.8M
Noninvasive MRI techniques to detect pathology in murine models of renal diseaseR01DK110622 · NIDDK · WASHINGTON UNIVERSITY · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2019
$1.0M
NCRR NIH HHS S10 RR019911NIDDK NIH HHS R01 DK110622NIDDK NIH HHS R01 DK111861
6 · The paper itself

Abstract

The development of chronic kidney disease (CKD) is associated with the loss of functional nephrons. However, there are no methods to directly measure nephron number in living subjects. Thus, there are no methods to track the early stages of progressive CKD before changes in total renal function. In this work, we used cationic ferritin-enhanced magnetic resonance imaging (CFE-MRI) to enable measurements of glomerular number (

Indexed as

AnimalsDisease ProgressionImage Processing, Computer-AssistedKidney DiseasesKidney GlomerulusMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLNephronsSignal-To-Noise RatioSyndactylycationic ferritinglomerulusmagnetic resonance imagingmousenephron numberoligosyndactylism

Identifiers

PMID31339774
PMCPMC6843043
OpenAlexW2963228224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.