ArticleHuman vaccines & immunotherapeutics2019
Cost-effectiveness of workplace vaccination against measles.
Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Measles among healthcare workers in Italy: is it time to act?Human vaccines & immunotherapeutics · 2020Pooled it
- Vaccine-Preventable Disease Outbreaks Among Healthcare Workers: A Scoping Review.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Questionable Immunity to Mumps among Healthcare Workers in Italy-A Cross-Sectional Serological Study.Vaccines · 2024Article
- Measles vaccine uptake among Italian medical students compared to the pre-COVID-19 era.Human vaccines & immunotherapeutics · 2023Observational
- Serological Evaluation for Measles among Italian and Foreign Medical Students in a University Hospital in Rome.Vaccines · 2023Article
- Global Policy to Reduce the Incidence of Infection Spreading in Non-Vaccinated Healthcare Workers: A Literature Review.Vaccines · 2022Review
- Barriers for vaccination of healthcare workers.Human vaccines & immunotherapeutics · 2021Article
- Article
- Seroprevalence for vaccine-preventable diseases among Italian healthcare workers.Human vaccines & immunotherapeutics · 2021Article
- Immunity to vaccine-preventable diseases among paediatric healthcare workers in Denmark, 2019.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021Article
- Seroprevalence survey for Varicella among healthcare workers and medical students in Italy.Human vaccines & immunotherapeutics · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measles is one of the most contagious infectious diseases. Measles vaccine, which has been introduced in Italy in 1979, is highly effective in preventing the disease (two-dose vaccine effectiveness is 99%). In 2017, Italy was the second country of EU for number of cases of measles. A study conducted in the same year showed that 22.3% of measles infection happened in hospital settings and 6.6% of cases occurred in HCWs. This risk group showed low rates of adhesion to the vaccination campaign. For this reason, we hypothesized that workplace vaccination could lead to better vaccination rates in HCWs. Moreover, we focused the vaccination campaign on a specific target group composed of HCWs not serologically immune and previously not vaccinated. We analyzed the clinical records of measles-specific IgG antibodies of 2,940 HCWs, that underwent occupational health surveillance between 1 January 2017 and 31 December 2017. 15.3% (450) was seronegative for measles, especially in the age group under 35 years. We compared the costs related to strategies with and without serological screening. Our study confirmed that immunization strategy with pre-vaccination screening was cost-effective compared to the vaccination without screening. In our sample, in fact, administration of two dose vaccine only susceptible HCWs determine a saving of 146,262 €. The vaccination of HCWs remains a topical issue in preventing the transmission of infectious disease in the hospital setting. Due to the cost-effectiveness evaluation, we recommend extending the pre-vaccination screening to identify the real susceptible workers.
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