Evidence map›Paper›PMID 31339356›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.

Brian D Hobbs, Rachel K Putman, Tetsuro Araki, Mizuki Nishino, Gunnar Gudmundsson, Vilmundur Gudnason, Gudny Eiriksdottir, Nuno Rodrigues Zilhao Nogueira, Josée Dupuis, Hanfei Xu and 32 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Article
  8. Pulmonary Fibrosis-Focusing on the Future: Aspen Lung Conference 2024 Summary.American journal of respiratory cell and molecular biology · 2025
    Article
  9. The role of theERJ open research · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Current perspectives on interstitial lung abnormalities.The Korean journal of internal medicine · 2025
    Review
  15. Review
  16. Article
  17. Genomic and Serological Rheumatoid Arthritis Biomarkers,Annals of the American Thoracic Society · 2025
    Article
  18. A Test to Comprehensively Capture the Known Genetic Component of Familial Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2024
    Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 3 countries.

Brian D HobbsChanning Division of Network Medicine.ORCID 0000-0001-9564-0745
Rachel K PutmanDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-8027-7450
Tetsuro ArakiDepartment of Radiology, and.
Mizuki NishinoDepartment of Radiology, and.
Gunnar GudmundssonDepartment of Respiratory Medicine, Landspital University Hospital, and.
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Gudny EiriksdottirIcelandic Heart Association, Kopavogur, Iceland.
Nuno Rodrigues Zilhao NogueiraIcelandic Heart Association, Kopavogur, Iceland.
Josée DupuisDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Hanfei XuDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
George T O'ConnorNHLBI Framingham Heart Study, Framingham, Massachusetts.
Ani ManichaikulCenter for Public Health Genomics.
Jennifer NguyenCenter for Public Health Genomics.
Anna J PodolanczukDepartment of Medicine, College of Physicians and Surgeons, and.ORCID 0000-0002-9559-1485
Purnema MadaharDepartment of Medicine, College of Physicians and Surgeons, and.
Jerome I RotterInstitute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, and.
David J LedererDepartment of Medicine, College of Physicians and Surgeons, and.ORCID 0000-0001-5258-0228
R Graham BarrDepartment of Medicine, College of Physicians and Surgeons, and.
Stephen S RichCenter for Public Health Genomics.
Elizabeth J AmplefordDepartment of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Victor E OrtegaDepartment of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Stephen P PetersDepartment of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Wanda K O'NealMarsico Lung Institute, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
John D NewellDivision of Cardiovascular and Pulmonary Imaging, Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Eugene R BleeckerDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona.
Deborah A MeyersDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona.
Richard J AllenDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Justin M OldhamDepartment of Internal Medicine, University of California Davis, Davis, California.
Shwu-Fan MaDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Imre NothDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
R Gisli JenkinsNational Institute for Health Research, Biomedical Research Centre, Respiratory Research Unit, School of Medicine, and.
Toby M MaherNational Institute for Health Research, Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom.
Richard B HubbardNational Institute for Health Research, Biomedical Research Centre, Respiratory Research Unit, School of Medicine, and.
Louise V WainNational Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom.
Tasha E FingerlinCenter for Genes, Environment and Health, National Jewish Health, Denver, Colorado; and.
David A SchwartzDepartment of Biostatistics and Informatics.
George R WashkoDivision of Pulmonary and Critical Care Medicine.
Ivan O RosasDivision of Pulmonary and Critical Care Medicine.
Edwin K SilvermanChanning Division of Network Medicine.
Hiroto HatabuDepartment of Radiology, and.
Michael H ChoChanning Division of Network Medicine.
Gary M HunninghakeDivision of Pulmonary and Critical Care Medicine.
Brigham and Women's Hospital · USPulmonary and Critical Care Associates · USRoyal College of Physicians · GBBoston University · USOffice of Public Health Genomics · USWake Forest University · USIcelandic Heart Association · ISNational Institute for Health Research · GBUniversity of Arizona · USUniversity of Virginia · USGlenfield Hospital · GBNational Jewish Health · USThe Lundquist Institute · USUniversity of California, Davis · USUniversity of Colorado Denver · USUniversity of Iceland · ISUniversity of Iowa · USUniversity of Leicester · GBUniversity of North Carolina at Chapel Hill · USUniversity of Nottingham · GB

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8M
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9M
Mechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLACKWELL, TIMOTHY S. · 2010 to 2020
$21.6M
MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Department of Health RP-2017-08-ST2-014HSRD VA CDA 13-017Medical Research Council G0901226Medical Research Council MR/N005953/1NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCI NIH HHS R01 CA203636NCI NIH HHS R33 CA182360NEI NIH HHS R01 EY009052NEI NIH HHS R01 EY023704NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K08 HL118128NHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08 HL140087NHLBI NIH HHS K23 HL138190NHLBI NIH HHS K23 HL140199NHLBI NIH HHS K24 HL131937NHLBI NIH HHS K24 HL137013NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS P01 HL092870NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132821NHLBI NIH HHS P01 HL136275NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01 HL097163NHLBI NIH HHS R01 HL103676NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL113264NHLBI NIH HHS R01 HL114587NHLBI NIH HHS R01 HL116473NHLBI NIH HHS R01 HL117843NHLBI NIH HHS R01 HL121270NHLBI NIH HHS R01 HL122464NHLBI NIH HHS R01 HL130796NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL131565NHLBI NIH HHS R01 HL133135NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01 HL137234NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL142028NHLBI NIH HHS R01 HL142302NHLBI NIH HHS R01 HL142992NHLBI NIH HHS R33 HL120770NHLBI NIH HHS T32 HL007085NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NHLBI NIH HHS U01 HL120393NHLBI NIH HHS U01 HL133232NHLBI NIH HHS U01 HL137880NHLBI NIH HHS U10 HL109164NHLBI NIH HHS U24 HL141762NHLBI NIH HHS UG1 HL139054NHLBI NIH HHS UH3 HL123442NIDDK NIH HHS DP3 DK111906NIDDK NIH HHS P30 DK063491NIH HHS OT2 OD026553NINR NIH HHS R01 NR013700
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Agedbeta KaryopherinsCase-Control StudiesFemaleGenetic LociGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansIdiopathic Pulmonary FibrosisLung Diseases, InterstitialMaleMiddle AgedMucin-5BPolymorphism, Single NucleotidePromoter Regions, GeneticTATA Box Binding Protein-Like Proteinsbeta KaryopherinsIPO11 protein, humanMUC5B protein, humanMucin-5BTATA Box Binding Protein-Like ProteinsTBPL1 protein, humangeneticsgenome-wide association studyidiopathic pulmonary fibrosisinterstitial lung abnormalitiesSNP

Identifiers

PMID31339356
PMCPMC6884045
OpenAlexW2958430756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.