ArticleKorean journal of radiology2019
Prognostic Value of Radiologic Extranodal Extension in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma.
Article in Korean journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Correlation between radiologic and pathologic extranodal extension in HPV-associated oropharyngeal cancer: Systematic review.Head & neck · 2022Pooled it
- The diagnostic performance of CT and MRI for detecting extranodal extension in patients with head and neck squamous cell carcinoma: a systematic review and diagnostic meta-analysis.European radiology · 2021Pooled it
- Article
- Multi-regional radiomics based on planning CT and information complementarity between GTVp and GTVn: an explainable model for predicting 5-year recurrence risk in HPV-positive oropharyngeal cancer.Radiation oncology (London, England) · 2026Article
- CT-based Extranodal Extension for Nodal Staging and Prognostic Stratification in Surgically Resectable Esophageal Squamous Cell Carcinoma.Radiology. Imaging cancer · 2026Observational
- Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma: Evolving Prognostic Markers, Molecular Insights, and Implications for Precision Staging.Diagnostics (Basel, Switzerland) · 2026Review
- [Clinical Significance of Extranodal Extension in Non-small Cell Lung Cancer: Current Status and Future Prospects].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026Review
- Imaging-Detected Extranodal Extension in Head and Neck Cancer: Clinical Significance and a Standardized Imaging Assessment.Journal of the Korean Society of Radiology · 2026Review
- MRI-detected extranodal extension as a marker of prostate cancer aggressiveness.European radiology · 2025Article
- PET/MR for predicting extranodal extension of head and neck cancer.Neuroradiology · 2025Article
- Observational
- Radiological extranodal extension in head and neck cancers: current evidence and challenges in imaging detection and prognostic impact.BJR open · 2025Review
- [Advances in the diagnosis and prognosis of extranodal extension in head and neck squamous cell carcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Review
- T2WI-based MRI radiomics for the prediction of preoperative extranodal extension and prognosis in resectable rectal cancer.Insights into imaging · 2024Article
- Unambiguous radiologic extranodal extension determined by MRI could be a biomarker in predicting metastatic prostate cancer.La Radiologia medica · 2023Article
- Diagnostic performance of computed tomography features in detecting oropharyngeal squamous cell carcinoma extranodal extension.European radiology · 2023Article
- Radiotherapy versus Surgery in Early-Stage HPV-Positive Oropharyngeal Cancer.Cancer research and treatment · 2022Article
- Differential expression of podoplanin in metastatic lymph node is associated with extranodal extension in oropharyngeal cancer.Scientific reports · 2022Article
- Mistakes to Avoid for Accurate and Transparent Reporting of Survival Analysis in Imaging Research.Korean journal of radiology · 2021Article
- Accuracy of the Anatomage Table in detecting extranodal extension in head and neck cancer: a pilot study.Journal of medical imaging (Bellingham, Wash.) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
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Abstract
objectiveTo determine whether radiologic extranodal extension (ENE) appearing on pretreatment CT and MRI could predict the prognosis in patients with human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC). MATERIALS AND
methodsThe study population was obtained from a historical cohort diagnosed with HPV-related OPSCC. A total of 134 OPSCC patients who had a metastatic lymph node on pretreatment CT or MRI were included, and radiologic ENE was evaluated by two experienced head and neck radiologists. Kaplan-Meier and multivariate Cox regression analyses were performed to evaluate the impact of radiologic ENE on progression-free survival (PFS). The diagnostic performance of CT and MRI for the diagnosis of ENE was also evaluated in patients who underwent neck dissection.
resultsSeventy patients (52.2%) showed radiologic ENE-positive findings. Although patients showing radiologic ENE had a worse 3-year PFS (83.7% vs. 95.3%,
conclusionRadiologic ENE on CT or MRI did not predict poor PFS in patients with HPV-related OPSCC, although there was a trend towards worse PFS. Further studies are warranted to determine whether radiologic ENE is a useful imaging biomarker to risk-stratify patients with HPV-related OPSCC.
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