Evidence map›Paper›PMID 31338963›Full record

ReviewEMBO reports2019

Microbial Experimental Evolution - a proving ground for evolutionary theory and a tool for discovery.

Michael J McDonald

Abstract readReview
In one paragraph

Review in EMBO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Studying adaptation at the invisible scale.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Adaptation and Plasticity ofEvolutionary applications · 2025
    Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael J McDonaldSchool of Biological Sciences, Monash University, Melbourne, Vic., Australia.ORCID 0000-0002-5735-960X

Funding

Department of Education and Training|Australian Research Council (ARC) DP180102161Department of Education and Training|Australian Research Council (ARC) FT170100441
6 · The paper itself

Abstract

Microbial experimental evolution uses controlled laboratory populations to study the mechanisms of evolution. The molecular analysis of evolved populations enables empirical tests that can confirm the predictions of evolutionary theory, but can also lead to surprising discoveries. As with other fields in the life sciences, microbial experimental evolution has become a tool, deployed as part of the suite of techniques available to the molecular biologist. Here, I provide a review of the general findings of microbial experimental evolution, especially those relevant to molecular microbiologists that are new to the field. I also relate these results to design considerations for an evolution experiment and suggest future directions for those working at the intersection of experimental evolution and molecular biology.

Indexed as

Biological EvolutionModels, GeneticAdaptation, PhysiologicalClone CellsDirected Molecular EvolutionEscherichia coliMolecular BiologyPseudomonas fluorescensSaccharomyces cerevisiaeSelection, Geneticadaptationdirected evolutionexperimental evolutionmicrobiome evolutionselection

Identifiers

PMID31338963
PMCPMC6680118

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.