Evidence map›Paper›PMID 31338796›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

New approach for quantification of left ventricular function from low-dose gated bloodpool SPECT: Validation and comparison with conventional methods in patients.

Yi-Hwa Liu, Ramesh Fazzone-Chettiar, Veronica Sandoval, Vera Tsatkin, Edward J Miller, Albert J Sinusas

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Routine first-line detection of breast cancer therapy-related cardiotoxicity by serial, fast and ultra-low-dose equilibrium radionuclide angiography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. Equilibrium radionuclide angiography: Present and future.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  4. Low-dose gated bloodpool SPECT: Is it time to make the shift?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Hwa LiuSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA. yi-hwa.liu@yale.edu.
Ramesh Fazzone-ChettiarDepartment of Nuclear Cardiology, Heart and Vascular Center, Yale New Haven Hospital, New Haven, CT, USA.
Veronica SandovalDepartment of Nuclear Cardiology, Heart and Vascular Center, Yale New Haven Hospital, New Haven, CT, USA.
Vera TsatkinDepartment of Nuclear Cardiology, Heart and Vascular Center, Yale New Haven Hospital, New Haven, CT, USA.
Edward J MillerSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA.
Albert J SinusasSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlanar equilibrium radionuclide angiocardiography (ERNA) has been used as the gold standard for assessment of left ventricular (LV) function for over three decades. However, this imaging modality has recently gained less favor due to growing concerns about radiation exposure. We developed a novel approach that involves integrating short axis slices of gated bloodpool SPECT for quantification of LV function with improved signal-to-noise ratio and reduced radioactive dose while maintaining image quality and quantitative precision.

methodsTwenty patients referred for ERNA underwent standard in vitro

resultsThe Yale method resulted in the most consistent assessment of LV function compared with the gold standard high-dose ERNA method, along with excellent inter-observer reproducibility.

conclusionsThe new low-dose

Indexed as

RadiopharmaceuticalsSodium Pertechnetate Tc 99mAgedCardiac-Gated Single-Photon Emission Computer-Assisted TomographyCoronary AngiographyFemaleGated Blood-Pool ImagingHumansMaleMiddle AgedPredictive Value of TestsReproducibility of ResultsStroke VolumeVentricular Dysfunction, LeftRadiopharmaceuticalsSodium Pertechnetate Tc 99mejection fractionERNAGated bloodpool SPECTleft ventricular volumes

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.