Evidence map›Paper›PMID 31338788›Full record

ArticleProbiotics and antimicrobial proteins2020

Characteristic of Bacteriocins of Lactobacillus rhamnosus BTK 20-12 Potential Probiotic Strain.

Flora N Tkhruni, Armen E Aghajanyan, Tsovinar R Balabekyan, Tatyana V Khachatryan, Kristina J Karapetyan

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A Bird's-Eye View of the Pathophysiologic Role of the Human Urobiota in Health and Disease: Can We Modulate It?Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. SARS-CoV-2 microbiome dysbiosis linked disorders and possible probiotics role.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Flora N TkhruniLaboratory of Biosafety of Food Products at Scientific and Production Center "Armbiotechnology" NSPO, National Academy of Science, 14 Gyurjyan Street, 0056, Yerevan, Republic of Armenia.
Armen E AghajanyanLaboratory of BAS Purification and Certification at Scientific and Production Center "Armbiotechnology" NSPO, National Academy of Science, 14 Gyurjyan Street, 0056, Yerevan, Republic of Armenia.
Tsovinar R BalabekyanLaboratory of Biosafety of Food Products at Scientific and Production Center "Armbiotechnology" NSPO, National Academy of Science, 14 Gyurjyan Street, 0056, Yerevan, Republic of Armenia.
Tatyana V KhachatryanLaboratory of Biosafety of Food Products at Scientific and Production Center "Armbiotechnology" NSPO, National Academy of Science, 14 Gyurjyan Street, 0056, Yerevan, Republic of Armenia.
Kristina J KarapetyanLaboratory of Biosafety of Food Products at Scientific and Production Center "Armbiotechnology" NSPO, National Academy of Science, 14 Gyurjyan Street, 0056, Yerevan, Republic of Armenia. kristinakarapetyan@mail.ru.
National Academy of Sciences of Armenia · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance (MDR) is a serious health threat throughout the world resulting in reduced efficacy of antibacterial, antiparasitic, antiviral, and antifungal drugs. One of the most promising concepts that may represent a good alternative to antibiotics can be the use of bacteriocins obtained from lactic acid bacteria. The L. rhamnosus BTK 20-12 strain was isolated from traditional Armenian naturally fermented salted cheese. The probiotic potential of the strain was approved. It was shown that strain produced at less two bacteriocins (BCN 1 and BCN 2) with different molecular weight (1427 Da and 602.6 Da, respectively). Bacteriocins inhibited the growth of multidrug-resistant bacteria of different etiologies and belong to different taxonomic groups with diverse efficiency and it depends on properties of bacteriocins, as well as from isolation sources of pathogens. Thus, bacteriocins of L. rhamnosus BTK 20-12 have protein-like nature and a broad range of activity and are excellent candidates for the development of new prophylactic and therapeutic substances to complement or replace conventional antibiotics.

Indexed as

ProbioticsAnti-Bacterial AgentsBacteriaBacteriocinsCheeseDrug Resistance, Multiple, BacterialFermented FoodsLacticaseibacillus rhamnosusAnti-Bacterial AgentsBacteriocinsAntibacterial activityBacteriocinHuman pathogensMultidrug resistance

Identifiers

PMID31338788
OpenAlexW2963718949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.