Evidence map›Paper›PMID 31338710›Full record

Observational studyTechniques in coloproctology2019

Effectiveness of endosponge therapy for the management of presacral abscesses following rectal surgery.

J F Huisman, H L van Westreenen, E J van der Wouden, H F A Vasen, E J R de Graaf, P G Doornebosch, T J Tang, I Schot, R M Brohet, W H de Vos Tot Nederveen Cappel and 1 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Article
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  6. Presacral tumors: A systematic review of literature.Journal of clinical imaging science · 2024
    Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J F HuismanDepartment of Gastroenterology and Hepatology, Isala, Zwolle, The Netherlands. j.f.huisman@isala.nl.ORCID http://orcid.org/0000-0002-4912-3306
H L van WestreenenDepartment of Surgery, Isala, Zwolle, The Netherlands.
E J van der WoudenDepartment of Gastroenterology and Hepatology, Isala, Zwolle, The Netherlands.
H F A VasenDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
E J R de GraafDepartment of Surgery, IJsselland Hospital, Capelle aan de IJssel, The Netherlands.
P G DoorneboschDepartment of Surgery, IJsselland Hospital, Capelle aan de IJssel, The Netherlands.
T J TangDepartment of Gastroenterology and Hepatology, IJsselland Hospital, Capelle aan de IJssel, The Netherlands.
I SchotDepartment of Gastroenterology and Hepatology, IJsselland Hospital, Capelle aan de IJssel, The Netherlands.
R M BrohetDepartment of Epidemiology and Statistics, Isala, Zwolle, The Netherlands.
W H de Vos Tot Nederveen CappelDepartment of Gastroenterology and Hepatology, Isala, Zwolle, The Netherlands.
M VermaasDepartment of Surgery, IJsselland Hospital, Capelle aan de IJssel, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnastomotic leak after rectal surgery is reported in 9% (range 3-28%) of patients. The aim of our study was to evaluate the effectiveness of endosponge therapy for anastomotic. Endpoints were the rate of restored continuity and the functional bowel outcome after anastomotic leakage.

methodsThis was a multicenter retrospective observational cohort study. All patients with symptomatic anastomotic leakage after rectal surgery who had endosponge therapy between January 2012 and August 2017 were included. Functional bowel outcome was measured using the low anterior resection syndrome (LARS) score system.

resultsTwenty patients were included. Eighteen patients had low anterior resection (90%) for rectal cancer. A diverting ileostomy was performed at primary surgical intervention in 14 patients (70%). Fourteen patients (70%) were treated with neoadjuvant (chemo-)radiotherapy. The median time between primary surgical intervention and first endosponge placement was 21 (5-537) days. The median number of endosponge changes was 9 (2-28). The success rate of the endosponge treatment was 88% and the restored gastrointestinal continuity rate was 73%. A chronic sinus occurred in three patients (15%). All patients developed LARS, of which 77% reported major LARS.

conclusionsEndosponge therapy is an effective treatment for the closure of presacral cavities with high success rate and leading to restored gastrointestinal continuity in 73%. However, despite endosponge therapy many patients develop major LARS.

Indexed as

Surgical SpongesAbscessAgedAnastomotic LeakEndoscopy, GastrointestinalFemaleHumansIleostomyMaleMiddle AgedPostoperative ComplicationsProctectomyRectal NeoplasmsRectumRetrospective StudiesSyndromeAnastomotic leakEndospongeLARS scorePatient reported outcome measuresRectal neoplasms

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.