Evidence map›Paper›PMID 31338623›Full record

ReviewMikrochimica acta2019

Aptamer and nanomaterial based FRET biosensors: a review on recent advances (2014-2019).

Zeki Semih Pehlivan, Milad Torabfam, Hasan Kurt, Cleva Ow-Yang, Niko Hildebrandt, Meral Yüce

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 146 citations in OpenAlex.

  1. Review
  2. EnterohemorrhagicACS omega · 2026
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  3. Article
  4. Review
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  13. Review
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  17. Review
  18. Article
  19. Capability of novel fluorescence DNA-conjugated CdTe/ZnS quantum dots nanoprobe for COVID-19 sensing.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zeki Semih PehlivanFaculty of Engineering and Natural Sciences, Sabanci University, 34956, Tuzla, Istanbul, Turkey.
Milad TorabfamFaculty of Engineering and Natural Sciences, Sabanci University, 34956, Tuzla, Istanbul, Turkey.
Hasan KurtSchool of Engineering and Natural Sciences, Istanbul Medipol University, 34810, Beykoz, Istanbul, Turkey.
Cleva Ow-YangFaculty of Engineering and Natural Sciences, Sabanci University, 34956, Tuzla, Istanbul, Turkey.
Niko HildebrandtNanoBioPhotonics (nanofret.com), Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Université Paris-Sud, CNRS, CEA, 91400, Orsay, France.
Meral YüceSUNUM Nanotechnology Research and Application Centre, Sabanci University, 34956, Tuzla, Istanbul, Turkey. meralyuce@sabanciuniv.edu.ORCID http://orcid.org/0000-0003-0393-1225
Sabancı Üniversitesi · TRGebze Technical University · TRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence resonance energy transfer, one of the most powerful phenomena for elucidating molecular interactions, has been extensively utilized as a biosensing tool to provide accurate information at the nanoscale. Numerous aptamer- and nanomaterial-based FRET bioassays has been developed for detection of a large variety of molecules. Affinity probes are widely used in biosensors, in which aptamers have emerged as advantageous biorecognition elements, due to their chemical and structural stability. Similarly, optically active nanomaterials offer significant advantages over conventional organic dyes, such as superior photophysical properties, large surface-to-volume ratios, photostability, and longer shelf life. In this report (with 175 references), the use of aptamer-modified nanomaterials as FRET couples is reviewed: quantum dots, upconverting nanoparticles, graphene, reduced graphene oxide, gold nanoparticles, molybdenum disulfide, graphene quantum dots, carbon dots, and metal-organic frameworks. Tabulated summaries provide the reader with useful information on the current state of research in the field. Graphical abstract Schematic representation of a fluorescence resonance energy transfer-based aptamer nanoprobe in the absence and presence of a given target molecule (analyte). Structures are not drawn to their original scales.

Indexed as

BiosensorsCarbon dotsFRETGold nanoparticlesGrapheneGraphene quantum dotsMetal-organic frameworkQuantum dotsReduced graphene oxidessDNAUp-converting nanoparticles

Identifiers

PMID31338623
OpenAlexW2963845446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.