ArticlePediatric nephrology (Berlin, Germany)2019
Kidney volume, kidney function, and ambulatory blood pressure in children born extremely preterm with and without nephrocalcinosis.
Article in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Kidney health outcomes in children born very prematurely compared to full-term counterparts: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Pooled it
- Kidney health and blood pressure after very preterm birth: a cohort study at school age.Pediatric nephrology (Berlin, Germany) · 2026Article
- Blood pressure trajectories in extreme preterm infants with and without bronchopulmonary dysplasia: a longitudinal cohort study.BMC pediatrics · 2026Article
- Renal consequences of prematurity and utility of serum uromodulin as a marker of kidney growth- a cross sectional single centre study.BMC nephrology · 2026Article
- The Link Between Preterm Birth and Long-Term Renal Consequences: Current Knowledge and Emerging Therapeutic Targets.Biomedicines · 2026Review
- Impact of growth hormone therapy on ambulatory blood pressure in small-for-gestational-age children.Annals of pediatric endocrinology & metabolism · 2026Article
- Early detection of kidney impairment in school-aged children born very preterm: a parallel use of traditional and modern biomarkers.Pediatric nephrology (Berlin, Germany) · 2026Article
- Reduced kidney function in very-low-birth-weight preterm infants at preschool age.Pediatric nephrology (Berlin, Germany) · 2025Article
- Kidney volume and function of low-birth-weight children at 5 years: impact of singleton and twin birth.Pediatric nephrology (Berlin, Germany) · 2025Article
- A Prospective Study of Nephrocalcinosis in Very Preterm Infants: Incidence, Risk Factors and Vitamin D Intake in the First Month.Medicina (Kaunas, Lithuania) · 2024Observational
- Etiology and prognosis of nephrocalcinosis according to gestational age in Korean children.BMC pediatrics · 2023Article
- Higher blood pressure in adolescent boys after very preterm birth and fetal growth restriction.Pediatric research · 2023Article
- Fetal growth restriction followed by very preterm birth is associated with smaller kidneys but preserved kidney function in adolescence.Pediatric nephrology (Berlin, Germany) · 2023Article
- Urinary KIM-1 is not correlated with gestational age among 5-year-old children born prematurely.Frontiers in pediatrics · 2023Article
- Nephrocalcinosis in very low birth weight infants: incidence, associated factors, and natural course.Pediatric nephrology (Berlin, Germany) · 2022Article
- Impaired renal clearance among Swedish adolescents born preterm.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Preterm Birth, Kidney Function and Cardiovascular Disease in Children and Adolescents.Children (Basel, Switzerland) · 2022Review
- Histologic characterization and risk factors for persistent albuminuria in adolescents in a region of highly prevalent end-stage renal failure of unknown origin.Clinical kidney journal · 2022Article
- Ambulatory Blood Pressure Monitoring in Children and Adolescents: 2022 Update: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReduced kidney volume (KV) following prematurity is a proxy for reduced nephron number and is associated with the development of hypertension and end-stage renal disease in adults. We investigated whether extreme prematurity affects KV, function, and blood pressure in school-aged children and if nephrocalcinosis (NC) developed during the neonatal period had additional effects.
methodsWe investigated 60 children at a mean age of 7.7 years: 20 born extremely preterm (EPT < 28 weeks gestational age with NC (NC+)), 20 born EPT without NC (NC-), and 19 born as full-term infants (control). We measured KV by ultrasound, collected blood and urine samples to evaluate renal function, and measured office and 24-h ambulatory blood pressure (ABPM).
resultsChildren born EPT had significantly smaller kidneys (EPT (NC+ NC-) vs control (estimated difference, 11.8 (CI - 21.51 to - 2.09 ml), p = 0.018) and lower but normal cystatin C-based glomerular filtration rate compared with control (estimated difference, - 10.11 (CI - 0.69 to - 19.5), p = 0.035). KV and function were not different between NC+ and NC- groups. Change in KV in relation to BSA (KV/BSA) from the neonatal period to school age showed significantly more EPT children with neonatal NC having a negative evolution of KV (p = 0.01). Blood pressure was normal and not different between the 3 groups. Fifty percent of EPT had a less than 10% day-to-night decline in ABPM.
conclusionsKidney growth and volume is affected by EPT birth with NC being a potential aggravating factor. Circadian blood pressure regulation seems abnormal in EPT-born children.
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