ArticleEuropean journal of hospital pharmacy : science and practice2019
Incompatible intravenous drug combinations and respective physician and nurse knowledge: a study in routine paediatric intensive care.
Article in European journal of hospital pharmacy : science and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 9 citations in OpenAlex.
- Clinical pharmacist-led prevention of intravenous drug incompatibilities in an adult ICU: a prospective observational study.BMC pharmacology & toxicology · 2026Observational
- Article
- Analysis of the Integrated Management Model of Medical Care and Medication in Intravenous Treatment for Critically Ill Patients.Journal of multidisciplinary healthcare · 2024Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesTo identify incompatible intravenous drug combinations in routine paediatric intensive care and evaluate physician and nurse knowledge.
methodsIn a university paediatric intensive care unit, intravenous drug incompatibilities were analysed using a database and physician and nurse knowledge of incompatibilities was assessed using a questionnaire.
resultsWe analysed 665 prescriptions in 87 patients. Incompatible drug administration was identified in 9 (10%) of the 87 patients with a median of 3 different incompatibilities per patient (Q25/Q75: 1/3). We found 26 incompatible combinations. The most frequently involved drugs were cefotaxime, pantoprazole and vancomycin. A median of 10 of the 15 drug combinations were correctly assessed as compatible or incompatible (Q25/Q75: 8/11). Pantoprazole had a low number (20%) of correct answers.
conclusionsOne in 10 patients in paediatric intensive care was affected by drug incompatibility, with knowledge deficits seen in a third of assessed combinations. This indicates quality improvement strategies should be urgently implemented by pharmacists.
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