ArticleFrontiers in genetics2019
Five-Feature Model for Developing the Classifier for Synergistic vs. Antagonistic Drug Combinations Built by XGBoost.
Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
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- Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose-Response Inference on hERG Inhibition Models.International journal of molecular sciences · 2022Article
- DIRECT-NET: An efficient method to discover cis-regulatory elements and construct regulatory networks from single-cell multiomics data.Science advances · 2022Article
- CDCDB: A large and continuously updated drug combination database.Scientific data · 2022Article
- Integrated Network Pharmacology Approach for Drug Combination Discovery: A Multi-Cancer Case Study.Cancers · 2022Article
- Machine learning methods, databases and tools for drug combination prediction.Briefings in bioinformatics · 2022Article
- m5Cpred-XS: A New Method for Predicting RNA m5C Sites Based on XGBoost and SHAP.Frontiers in genetics · 2022Article
- Predicting the risk of nodular thyroid disease in coal miners based on different machine learning models.Frontiers in medicine · 2022Article
- Time series analysis of hemorrhagic fever with renal syndrome in mainland China by using an XGBoost forecasting model.BMC infectious diseases · 2021Article
- Quantitative profiling of NGenome biology · 2021Article
- Machine Learning for Predicting the 3-Year Risk of Incident Diabetes in Chinese Adults.Frontiers in public health · 2021Article
- Ability of a Machine Learning Algorithm to Predict the Need for Perioperative Red Blood Cells Transfusion in Pelvic Fracture Patients: A Multicenter Cohort Study in China.Frontiers in medicine · 2021Article
- Evaluating DNA Methylation, Gene Expression, Somatic Mutation, and Their Combinations in Inferring Tumor Tissue-of-Origin.Frontiers in cell and developmental biology · 2021Article
- Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma.Frontiers in pharmacology · 2021Article
- Diagnostic Value of the Fimbriae Distribution Pattern in Localization of Urinary Tract Infection.Frontiers in medicine · 2021Article
- Identification of Orphan Genes in Unbalanced Datasets Based on Ensemble Learning.Frontiers in genetics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combinatorial drug therapy can improve the therapeutic effect and reduce the corresponding adverse events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.