Evidence map›Paper›PMID 31338034›Full record

ReviewFrontiers in pharmacology2019

Jie Ren, Li Fu, Shivraj Hariram Nile, Jun Zhang, Guoyin Kai

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04395547 (A Randomized, Double-blind, Placebo-controlled, Parallel Study to Investigate the Safety and Efficacy of JointAlive™ on Improving Knee Joint Function in Adults With Mild to Moderate Knee Osteoarthritis), which is not on this map. Cited by 132 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04395547 nacompletednot on this mapstarted 2020, after this paper: background citation

A Randomized, Double-blind, Placebo-controlled, Parallel Study to Investigate the Safety and Efficacy of JointAlive™ on Improving Knee Joint Function in Adults With Mild to Moderate Knee Osteoarthritis

TypeinterventionalSponsorChenland Nutritionals Inc.Ran2020 to 2022Enrolled72ConditionsOsteo Arthritis KneeArmsJointAlive™, Placebo
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Phenolic and Terpenic Composition ofPlants (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Title-effectiveness and safety of Danshen injection for acute kidney injury in primary nephrotic syndrome.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie RenInstitute of Plant Biotechnology, School of Life Sciences, Shanghai Normal University, Shanghai, China.
Li FuInstitute of Plant Biotechnology, School of Life Sciences, Shanghai Normal University, Shanghai, China.
Shivraj Hariram NileLaboratory of Medicinal Plant Biotechnology, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Jun ZhangInstitute of Plant Biotechnology, School of Life Sciences, Shanghai Normal University, Shanghai, China.
Guoyin KaiInstitute of Plant Biotechnology, School of Life Sciences, Shanghai Normal University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive chemical constitutes from the root of

Indexed as

antioxidativeatherosclerosiscardiovascular diseasesendothelial protectivemyocardial infarctionSalvia miltiorrhiza

Identifiers

PMID31338034
PMCPMC6626924

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.