Evidence map›Paper›PMID 31338005›Full record

ReviewEXCLI journal2019

Cell junctions and oral health.

Mohammad Samiei, Elham Ahmadian, Aziz Eftekhari, Mohammad Ali Eghbal, Fereshte Rezaie, Mathieu Vinken

Abstract readReview
In one paragraph

Review in EXCLI journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Metabolic modulation and multi-species interaction:Frontiers in cellular and infection microbiology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. The Role of the Innate Immune Response in Oral Mucositis Pathogenesis.International journal of molecular sciences · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. An Overview of Physical, Microbiological and Immune Barriers of Oral Mucosa.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad SamieiFaculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Elham AhmadianDental and Periodontal Research center, Tabriz University of Medical Sciences, Tabriz, Iran.
Aziz EftekhariPharmacology and Toxicology department, Maragheh University of Medical Sciences, Maragheh, Iran.
Mohammad Ali EghbalDrug Applied Research Center and Pharmacology and Toxicology department, Tabriz University of Medical Sciences, Tabriz, Iran.
Fereshte RezaieGeneral Practitioner, Tabriz University of Medical Sciences, Tabriz, Iran.
Mathieu VinkenDepartment of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral cavity and its appendices are exposed to considerable environmental and mechanical stress. Cell junctions play a pivotal role in this context. Among those, gap junctions permit the exchange of compounds between cells, thereby controlling processes such as cell growth and differentiation. Tight junctions restrict paracellular transportation and inhibit movement of integral membrane proteins between the different plasma membrane poles. Adherens junctions attach cells one to another and provide a solid backbone for resisting to mechanistical stress. The integrity of oral mucosa, normal tooth development and saliva secretion depend on the proper function of all these types of cell junctions. Furthermore, deregulation of junctional proteins and/or mutations in their genes can alter tissue functioning and may result in various human disorders, including dental and periodontal problems, salivary gland malfunction, hereditary and infectious diseases as well as tumorigenesis. The present manuscript reviews the role of cell junctions in the (patho)physiology of the oral cavity and its appendices, including salivary glands.

Indexed as

anchoring junctiongap junctionoral diseaseoral healthtight junction

Identifiers

PMID31338005
PMCPMC6635732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.