Evidence map›Paper›PMID 31337981›Full record

ArticleInternational journal of biological sciences2019

The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer.

Chao Dong, Yin Chen, Hongjian Li, Yi Yang, Hongtao Zhang, Kunbin Ke, Xi-Nan Shi, Xu Liu, Ling Li, Jing Ma and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Chao DongDepartment of the second medical oncology, The 3rd Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, China.
Yin ChenDepartment of Urology, the 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Hongjian LiSDIVF R&D Centre, Hong Kong Science Park, Sha Tin, New Territories, Hong Kong.
Yi YangDepartment of the radiation oncology, The 3rd Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, China.
Hongtao ZhangDepartment of the colorectal surgery, The 3rd Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, China.
Kunbin KeDepartment of Urology, the 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Xi-Nan ShiDepartment of Pathophysiology, School of Basic Medical Sciences, Yunnan University of TCM, Kunming, China.
Xu LiuBiomedical Engineering Research Center, Kunming Medical University, Kunming, Yunnan, China.
Ling LiBiomedical Engineering Research Center, Kunming Medical University, Kunming, Yunnan, China.
Jing MaDepartment of Otolaryngology, Head and Neck Surgery, Kunming Children's Hospital, Kunming, China.
Hsiang-Fu KungBiomedical Engineering Research Center, Kunming Medical University, Kunming, Yunnan, China.
Ceshi ChenKey Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Marie Chia-Mi LinInstitute of Medical and Pharmaceutical Sciences, The Academy of Medical Science, Zhengzhou University, Zhengzhou, China.
Kunming Medical University · CNChinese University of Hong Kong · CNKunming Institute of Zoology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

A549 CellsAnimalsAntineoplastic AgentsAntipsychotic AgentsApoptosisCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationFlupenthixolHumansLung NeoplasmsMaleMiceMice, Inbred BALB CMice, NudeMolecular Docking SimulationAntineoplastic AgentsAntipsychotic AgentsFlupenthixolPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsFlupentixolLung cancerPI3K inhibitorPI3Kα

Identifiers

PMID31337981
PMCPMC6643147
OpenAlexW2951160992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.