Evidence map›Paper›PMID 31337979›Full record

ArticleInternational journal of biological sciences2019

Scutellaria Flavonoids Effectively Inhibit the Malignant Phenotypes of Non-small Cell Lung Cancer in an Id1-dependent Manner.

Zhengxiao Zhao, Baojun Liu, Jing Sun, Linwei Lu, Lumei Liu, Jian Qiu, Qiuping Li, Chen Yan, Shan Jiang, Nabijan Mohammadtursun and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Zhengxiao ZhaoDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Baojun LiuDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Jing SunDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Linwei LuDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Lumei LiuDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Jian QiuDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Qiuping LiDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Chen YanDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Shan JiangDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Nabijan MohammadtursunDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Wenjuan MaDepartment of dermatology, Huashan Hospital, Fudan University, Shanghai, PR China.
Mihui LiDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Jingcheng DongDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Weiyi GongDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, PR China.
Fudan University · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the world. Inhibitor of differentiation 1 (Id1) is overexpressed in NSCLC and involved in promoting its progression and metastasis. Identifying natural compounds targeting Id1 may have utility in NSCLC treatment. Here, we sought to determine whether the anti-tumor activities of

Indexed as

A549 Cellsalpha7 Nicotinic Acetylcholine ReceptorAnimalsAntineoplastic AgentsCarcinoma, Non-Small-Cell LungCell Line, TumorCell MovementCell ProliferationCell SurvivalFlavanonesFlavonoidsGuanosine TriphosphateHumansInhibitor of Differentiation Protein 1Lung NeoplasmsMalealpha7 Nicotinic Acetylcholine ReceptorAntineoplastic AgentsbaicaleinbaicalinFlavanonesFlavonoidsGuanosine TriphosphateID1 protein, humanIdb1 protein, mouseInhibitor of Differentiation Protein 1Plant ExtractsShelterin ComplexTelomere-Binding ProteinsTERF2IP protein, humanwogoninalpha 7 nicotinic acetylcholine receptor (α7nAChR)inhibitor of differentiation 1 (Id1)non-small cell lung cancer (NSCLC)scutellaria flavonoids (SFs)

Identifiers

PMID31337979
PMCPMC6643150
OpenAlexW2951729569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.